Diabetes mellitus is a major health concern, affecting more than 5% of the population. Here
we describe a potential novel therapeutic agent for this disease, FGF-21, which was …

Uncontrolled hepatic glucose production contributes significantly to hyperglycemia in patients
with type 2 diabetes. Hyperglucagonemia is implicated in the etiology of this condition; …

A process based on reversed-phase high-performance liquid chromatography (RP-HPLC)
has been developed for the purification of biosynthetic human insulin (BHI). The RP-HPLC …

Syndecan-1 (CD138) mediates myeloma cell adhesion, and loss of syndecan-1 from the cell
surface may contribute to myeloma proliferation and dissemination. Flow cytometry analysis …

Gliotoxin is a redox-active nonribosomal peptide produced by Aspergillus fumigatus. Like
many other disulfide-containing epipolythiodioxopiperazines, a bis-thiomethylated form is also …

Glycogen synthase kinase-3 (GSK3) is involved in signaling from the insulin receptor.
Inhibitors of GSK3 are expected to effect lowering of plasma glucose similar to insulin, making …

Purpose This study investigated the predictive value of practice-related variables—number
of treatment trials delivered, total treatment time, average number of trials per hour, and …

The Phytophthora genus includes some of the most devastating plant pathogens. Here we
report draft genome sequences for three ubiquitous Phytophthora species—Phytophthora …

This study shows that breathing mindfully for 3 minutes over a period of 4 weeks, positively
affects compassion fatigue in nurses. A nonrandomized, pre/postintervention study was …

The function of a number of genes in the gliotoxin biosynthetic cluster (gli) in Aspergillus
fumigatus remains unknown. Here, we demonstrate that gliK deletion from two strains of A. …