User profiles for Rebecca Elyanow
Rebecca ElyanowAdaptive Biotechnologies Verified email at adaptivebiotech.com Cited by 611 |
[HTML][HTML] Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels
…, Q DeGottardi, G Keitany, J Lu, A Vong, R Elyanow… - MedRxiv, 2020 - ncbi.nlm.nih.gov
T cells are involved in the early identification and clearance of viral infections and also
support the development of antibodies by B cells. This central role for T cells makes them a …
support the development of antibodies by B cells. This central role for T cells makes them a …
[HTML][HTML] T cell receptor sequencing identifies prior SARS-CoV-2 infection and correlates with neutralizing antibodies and disease severity
BACKGROUND Measuring the immune response to SARS-CoV-2 enables assessment of
past infection and protective immunity. SARS-CoV-2 infection induces humoral and T cell …
past infection and protective immunity. SARS-CoV-2 infection induces humoral and T cell …
The T-cell response to SARS-CoV-2 vaccination in inflammatory bowel disease is augmented with anti-TNF therapy
Lay Summary T-cell and antibody responses to severe acute respiratory syndrome
coronavirus 2 vaccination in inflammatory bowel disease patients are poorly correlated. T-cell …
coronavirus 2 vaccination in inflammatory bowel disease patients are poorly correlated. T-cell …
Identifying structural variants using linked-read sequencing data
Motivation Structural variation, including large deletions, duplications, inversions, translocations
and other rearrangements, is common in human and cancer genomes. A number of …
and other rearrangements, is common in human and cancer genomes. A number of …
netNMF-sc: leveraging gene–gene interactions for imputation and dimensionality reduction in single-cell expression analysis
Single-cell RNA-sequencing (scRNA-seq) enables high-throughput measurement of RNA
expression in single cells. However, because of technical limitations, scRNA-seq data often …
expression in single cells. However, because of technical limitations, scRNA-seq data often …
Symptom burden and immune dynamics 6 to 18 months following mild severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2): a case-control study
…, TB Onyango, KA Brokstad, R Elyanow… - Clinical Infectious …, 2023 - academic.oup.com
Background The burden and duration of persistent symptoms after nonsevere coronavirus
disease 2019 (COVID-19) remains uncertain. This study aimed to assess postinfection …
disease 2019 (COVID-19) remains uncertain. This study aimed to assess postinfection …
AIRIVA: a deep generative model of adaptive immune repertoires
Recent advances in immunomics have shown that T-cell receptor (TCR) signatures can
accurately predict active or recent infection by leveraging the high specificity of TCR binding to …
accurately predict active or recent infection by leveraging the high specificity of TCR binding to …
STARCH: copy number and clone inference from spatial transcriptomics data
Tumors are highly heterogeneous, consisting of cell populations with both transcriptional
and genetic diversity. These diverse cell populations are spatially organized within a tumor, …
and genetic diversity. These diverse cell populations are spatially organized within a tumor, …
[HTML][HTML] Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection
T cells play a prominent role in orchestrating the immune response to viral diseases, but
their role in the clinical presentation and subsequent immunity to SARS-CoV-2 infection …
their role in the clinical presentation and subsequent immunity to SARS-CoV-2 infection …
Immunosequencing and epitope mapping reveal substantial preservation of the T cell immune response to Omicron generated by SARS-CoV-2 vaccines
The Omicron SARS-CoV-2 variant contains 34 mutations in the spike gene likely impacting
protective efficacy from vaccines. We evaluated the potential impact of these mutations on the …
protective efficacy from vaccines. We evaluated the potential impact of these mutations on the …