User profiles for Rebecca L. Skalsky

Rebecca L. Skalsky

Oregon Health and Science University
Verified email at ohsu.edu
Cited by 5275

Viruses, microRNAs, and host interactions

RL Skalsky, BR Cullen - Annual review of microbiology, 2010 - annualreviews.org
One of the most significant recent advances in biomedical research has been the discovery
of the ∼22-nt-long class of noncoding RNAs designated microRNAs (miRNAs). These …

Kaposi's sarcoma-associated herpesvirus encodes an ortholog of miR-155

RL Skalsky, MA Samols, KB Plaisance, IW Boss… - Journal of …, 2007 - Am Soc Microbiol
MicroRNAs (miRNAs) are small noncoding RNAs that posttranscriptionally regulate gene
expression by binding to 3′-untranslated regions (3′UTRs) of target mRNAs. Kaposi's …

Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus

MA Samols, J Hu, RL Skalsky, R Renne - Journal of virology, 2005 - Am Soc Microbiol
MicroRNAs (miRNAs) are small, noncoding regulatory RNA molecules that bind to 3′
untranslated regions (UTRs) of mRNAs to either prevent their translation or induce their …

[HTML][HTML] The viral and cellular microRNA targetome in lymphoblastoid cell lines

RL Skalsky, DL Corcoran, E Gottwein, CL Frank… - PLoS …, 2012 - journals.plos.org
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell
cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-…

[HTML][HTML] PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data

…, S Georgiev, N Mukherjee, E Gottwein, RL Skalsky… - Genome biology, 2011 - Springer
Crosslinking and immunoprecipitation (CLIP) protocols have made it possible to identify
transcriptome-wide RNA-protein interaction sites. In particular, PAR-CLIP utilizes a …

[HTML][HTML] Identification of cellular genes targeted by KSHV-encoded microRNAs

MA Samols, RL Skalsky, AM Maldonado, A Riva… - PLoS …, 2007 - journals.plos.org
MicroRNAs (miRNAs) are 19 to 23 nucleotide–long RNAs that post-transcriptionally regulate
gene expression. Human cells express several hundred miRNAs which regulate important …

[PDF][PDF] Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines

E Gottwein, DL Corcoran, N Mukherjee, RL Skalsky… - Cell host & …, 2011 - cell.com
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus (KSHV)
and frequently also harbors Epstein-Barr virus (EBV). The expression of KSHV- and …

Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus

SD Linnstaedt, E Gottwein, RL Skalsky… - Journal of …, 2010 - Am Soc Microbiol
Infection of resting primary human B cells by Epstein-Barr virus (EBV) results in their
transformation into indefinitely proliferating lymphoblastoid cell lines (LCLs). LCL formation serves …

[HTML][HTML] Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus

RL Skalsky, DL Vanlandingham, F Scholle, S Higgs… - BMC genomics, 2010 - Springer
Background MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally
regulate gene expression in a variety of organisms, including insects, vertebrates, and plants. …

[HTML][HTML] Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene

RL Skalsky, BR Cullen - PloS one, 2011 - journals.plos.org
Glioblastoma is a highly aggressive malignant tumor involving glial cells in the human brain.
We used high-throughput sequencing to comprehensively profile the small RNAs …