[HTML][HTML] Interventions to improve well-being among children and youth aged 6–17 years during the COVID-19 pandemic: a systematic review

SJ Moss, SJ Mizen, M Stelfox, RB Mather… - BMC medicine, 2023 - Springer
Background The COVID-19 pandemic is an example of a global infectious disease outbreak
that poses a threat to the well-being of children and youth (eg, physical infection, …

The evolutionarily conserved long non‐coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and …

RL Mather, A Parolia, SE Carson… - Molecular …, 2021 - Wiley Online Library
Metastatic neuroendocrine prostate cancer (NEPC) is a highly aggressive disease, whose
incidence is rising. Long noncoding RNAs (lncRNAs) represent a large family of disease‐ and …

Childhood poverty, adverse childhood experiences, and adult health outcomes

H Lee, KS Slack, LM Berger, RS Mather… - Health & Social …, 2021 - academic.oup.com
This study aimed to consider childhood poverty in relation to a count measure of adverse
childhood experiences (ACEs) as a predictor of adult health outcomes and to determine …

The long noncoding RNA HORAS5 mediates castration‐resistant prostate cancer survival by activating the androgen receptor transcriptional program

A Parolia, E Venalainen, H Xue, R Mather… - Molecular …, 2019 - Wiley Online Library
Prostate cancer ( PC a) is driven by the androgen receptor ( AR )‐signaling axis. Hormonal
therapy often mitigates PC a progression, but a notable number of cases progress to …

LncRNA HORAS5 promotes taxane resistance in castration-resistant prostate cancer via a BCL2A1-dependent mechanism

…, I Alborelli, L Quagliata, C Hawkes, R Mather… - …, 2020 - Future Medicine
Background: Castration-resistant prostate cancer (CRPC) is an incurable malignancy. Long
noncoding RNAs (lncRNAs) play key roles in drug resistance. Materials & methods: LncRNA …

T‐type calcium channels drive the proliferation of androgen‐receptor negative prostate cancer cells

…, P Pucci, E Venalainen, C Matheou, R Mather… - The …, 2019 - Wiley Online Library
Background Androgen deprivation therapy (ADT) is the treatment of choice for metastatic
prostate cancer (PCa). After an initial response to ADT, PCa cells can generate castration …

[HTML][HTML] Human Sialic acid O-acetyl esterase (SIAE) – mediated changes in sensitivity to etoposide in a medulloblastoma cell line

RL Mather, KF Loveson, HL Fillmore - Scientific Reports, 2019 - nature.com
Medulloblastoma (MB), the most common malignant paediatric brain tumour occurs in the
cerebellum. Advances in molecular genomics have led to the identification of defined …

[HTML][HTML] The long non-coding RNA H19 drives the proliferation of diffuse intrinsic pontine glioma with H3K27 mutation

…, H Jackson, KF Loveson, A Mackay, RL Mather… - International Journal of …, 2021 - mdpi.com
Diffuse intrinsic pontine glioma (DIPG) is an incurable paediatric malignancy. Identifying the
molecular drivers of DIPG progression is of the utmost importance. Long non-coding RNAs (…

Adverse childhood experiences, positive childhood experiences, and adult health

H Lee, R Boyd, KS Slack, RS Mather… - Journal of the Society …, 2022 - journals.uchicago.edu
Objective: This study investigates the associations between positive childhood experiences
and adult well-being, examining the moderating role of childhood social support in the …

Is HOTAIR really involved in neuroendocrine prostate cancer differentiation?

RL Mather, Y Wang, F Crea - Epigenomics, 2018 - Taylor & Francis
Long noncoding RNAs (lncRNAs) are emerging as key players in several aspects of human
pathophysiology [4]. Upon transcription, lncRNAs fold in tridimensional structures and can …