CDK4/6 inhibitors arrest the cell cycle in G1‐phase. They are approved to treat breast cancer
and are also undergoing clinical trials against a range of other tumour types. To facilitate …

CDK4/6 inhibitors are remarkable anti-cancer drugs that can arrest tumor cells in G1 and
induce their senescence while causing only relatively mild toxicities in healthy tissues. How …

Abnormal increases in cell size are associated with senescence and cell cycle exit. The
mechanisms by which overgrowth primes cells to withdraw from the cell cycle remain unknown. …

CDK4/6 inhibitors are effective at treating advanced HR+/HER2-breast cancer, however
biomarkers that can predict response are urgently needed. We demonstrate here that previous …

Cell size and the cell cycle are intrinsically coupled and abnormal increases in cell size are
associated with senescence. The mechanism by which overgrowth primes cells to exit the …

… Gertie Reece Foy lives with her great-aunt Rae in coastal Alabama while her kind and … ..
.and then Rachel Collins would know that Gertie Foy was one-hundred-percent, not-from-…

… He hunkered in the dark culvert under the driveway and gazed at Gertie Reece Foy with a
tragical gleam in his eye, as if he knew that her face was the last lovely thing he would ever …

Colorism research often suffers from endogeneity issues related to human capital outcomes
and researchers’ inability to compare the effects of skin tone to those of racial classification. …

Modeling has enabled fundamental advances in our understanding of the mechanisms of
health and disease for centuries, since at least the time of William Harvey almost 500 years …

Today libraries stand as the most inclusive institution in US society, but their workforces
remain unaligned with the wide-ranging domestic demographic. With 83% of librarians …