Deciphering the immunomodulatory capacity of oncolytic vaccinia virus to enhance the immune response to breast cancer

…, BC Franczak, MM Shenouda, RG Kelly… - Cancer Immunology …, 2020 - AACR
… mashed through a 70-μm cell strainer into isolation buffer [PBS + 2% heat-inactivated FBS
(HI-FBS) + 0.5 mmol/L EDTA] using the rubber end of a 3 mL syringe, centrifuged at 300 × g

γδ thymocyte maturation and emigration in adult mice

…, LM Henao-Caviedes, JF May, RG Kelly… - The Journal of …, 2022 - journals.aai.org
Several unique waves of γδ T cells are generated solely in the fetal/neonatal thymus, whereas
additional γδ T cell subsets are generated in adults. One intriguing feature of γδ T cell …

Establishment of CD8+ T cell thymic central tolerance to tissue-restricted antigen requires PD-1

JF May, RG Kelly, AYW Suen, J Kim, J Kim… - The Journal of …, 2024 - journals.aai.org
Highly self-reactive T cells are censored from the repertoire by both central and peripheral
tolerance mechanisms upon receipt of high-affinity TCR signals. Clonal deletion is considered …

258-LB: Vitamin D Directly Regulates TRPV1 Channel Activity and May Play an Important Role in the Autoimmune Disease of Type 1 Diabetes

W Long, M Fatehi, S Soni, R Panigrahi, RG Kelly… - Diabetes, 2019 - Am Diabetes Assoc
The autoimmune disease of type 1 diabetes (T1D) results in the immune destruction of β-cells.
Recent studies suggest supplementation of vitamin D along can significantly improve …

Predicting conversion to wet age-related macular degeneration using deep learning

…, C Meyer, M Wilson, J Dixon, C Hughes, G Rees… - Nature Medicine, 2020 - nature.com
Progression to exudative ‘wet’ age-related macular degeneration (exAMD) is a major cause
of visual deterioration. In patients diagnosed with exAMD in one eye, we introduce an …

[HTML][HTML] Clinically applicable segmentation of head and neck anatomy for radiotherapy: deep learning algorithm development and validation study

…, K Hampton, K Fuller, H Montgomery, G Rees… - Journal of medical …, 2021 - jmir.org
Background Over half a million individuals are diagnosed with head and neck cancer each
year globally. Radiotherapy is an important curative treatment for this disease, but it requires …

Deep learning to achieve clinically applicable segmentation of head and neck anatomy for radiotherapy

…, K Hampton, K Fuller, H Montgomery, G Rees… - arXiv preprint arXiv …, 2018 - arxiv.org
Over half a million individuals are diagnosed with head and neck cancer each year worldwide.
Radiotherapy is an important curative treatment for this disease, but it requires manual …

[HTML][HTML] Application of Nitrogen and Carbon Stable Isotopes (δ15N and δ13C) to Quantify Food Chain Length and Trophic Structure

…, RA McDonald, FJF van Veen, SD Kelly, G Rees… - PloS one, 2014 - journals.plos.org
Increasingly, stable isotope ratios of nitrogen (δ 15 N) and carbon (δ 13 C) are used to quantify
trophic structure, though relatively few studies have tested accuracy of isotopic structural …

Facile silane functionalization of graphene oxide

SS Abbas, GJ Rees, NL Kelly, CEJ Dancer, JV Hanna… - Nanoscale, 2018 - pubs.rsc.org
Rees b , Nicole L. Kelly b , Claire EJ Dancer ORCID logo a , John V. Hanna ORCID logo b …
As GO is reduced the G band shifts from 1595 cm −1 to 1590 cm −1 , which is similar to that for …

Verifying the geographical origin of poultry: The application of stable isotope and trace element (SITE) analysis

G Rees, SD Kelly, P Cairns, H Ueckermann, S Hoelzl… - Food Control, 2016 - Elsevier
Stable isotope and elemental analysis, together with statistical processing of the resultant
data has been used to determine the geographical origin of poultry and hence provide a …