Carbon catabolite repression (CCR) in bacteria is generally regarded as a regulatory
mechanism to ensure sequential utilization of carbohydrates. Selection of the carbon sources is …

A system for high-efficiency gene replacement in Staphylococcus carnosus and Staphylococcus
xylosus has been developed, that is based on temperature-sensitive Escherichia coli–…

Streptococcus pneumoniae is one of the few species within the group of low-G +C gram-positive
bacteria reported to contain no d-alanine in teichoic acids, although the dltABCD …

Alterations in the target enzymes for β-lactam antibiotics, the penicillin-binding proteins (PBPs),
have been recognized as a major resistance mechanism in Streptococcus pneumoniae. …

The two‐component regulatory system CiaRH of Streptococcus pneumoniae has been
implicated in β‐lactam resistance, maintenance of cell integrity, competence and virulence, but …

The cell wall of Streptococcus pneumoniae contains an unusually complex wall teichoic acid
(WTA), which has identical repeating units as the membrane-anchored lipoteichoic acid (…

Glucose is the classical carbon source that is used to investigate the transport, metabolism,
and regulation of nutrients in bacteria. Many physiological phenomena like nutrient limitation, …

Streptococcus mitis is the closest relative of the major human pathogen S. pneumoniae. The
2,15 Mb sequence of the Streptococcus mitis B6 chromosome, an unusually high-level beta-…

The pneumococcal choline-containing teichoic acids are targeted by choline-binding
proteins (CBPs), major surface components implicated in the interaction with host cells and …

Small regulatory RNAs (sRNAs) that act by base-pairing were first discovered in so-called
accessory DNA elements—plasmids, phages, and transposons—where they control …