Invertebrates, particularly sponges, have been a dominant source of new marine natural
products. For example, lasonolide A (LSA) is a potential anticancer molecule isolated from the …

The genome sequence of the Forcepia sponge-derived bacterium Streptomyces sp. strain
HB-N217 was determined, with approximately 8.25 Mbp and a G+C content of 72.1%. Thirty …

… René KM Xavier iii A SHOTGUN METAGENOMIC APPROACH TO THE BIOSYNTHESIS OF
MARINE NATURAL PRODUCTS by René KM Xavier … v ABSTRACT Author: René KM Xavier …

Introduction: Non-communicable diseases (NCDs) are on the rise in sub-Saharan Africa. The
overall objective of this study was to estimate the prevalence of behavioural risk factors for …

… This study assesses the vulnerable state of the 566-km Ivorian coastal area using the
physical (geomorphology, coastal slope, coastal retreat rate, relative sea level rise and wave/Tide …

Importance Although tumor necrosis factor (TNF) inhibitors are widely prescribed globally
because of their ability to ameliorate shared immune pathways across immune-mediated …

Hybridisation between wild taxa and their domestic congeners is a significant conservation
issue. Domestic species frequently outnumber their wild relatives in population size and …

… of the studied areas (more than 16 inhabitants per km 2 ) and a high urbanization rate [19]. …
a low population density (less than 1 inhabitant/km 2 ). It contains the Amazon River valley, …

Home range estimation is routine practice in ecological research. While advances in animal
tracking technology have increased our capacity to collect data to support home range …

Objectives Janus kinase inhibitors (JAKi) have been approved for use in various immune-mediated
inflammatory diseases. With five agents licensed, it was timely to summarise the …