Mammalian UPF3A and UPF3B can activate nonsense‐mediated mRNA decay independently of their exon junction complex binding
Z Yi, RM Arvola, S Myers, CN Dilsavor… - The EMBO …, 2022 - embopress.org
Nonsense‐mediated mRNA decay (NMD) is governed by the three conserved factors—UPF1,
UPF2, and UPF3. While all three are required for NMD in yeast, UPF3B is dispensable for …
UPF2, and UPF3. While all three are required for NMD in yeast, UPF3B is dispensable for …
Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio
CA Weidmann, C Qiu, RM Arvola, TF Lou… - Elife, 2016 - elifesciences.org
10.7554/eLife.17096.001 Collaboration among the multitude of RNA-binding proteins (RBPs)
is ubiquitous, yet our understanding of these key regulatory complexes has been limited to …
is ubiquitous, yet our understanding of these key regulatory complexes has been limited to …
Combinatorial control of messenger RNAs by Pumilio, Nanos and brain tumor proteins
RM Arvola, CA Weidmann, TM Tanaka Hall… - RNA biology, 2017 - Taylor & Francis
… René M. Arvola is supported by graduate research fellowship DGE 1256260 from the National
Science Foundation. We sincerely apologize to colleagues whose work we were unable …
Science Foundation. We sincerely apologize to colleagues whose work we were unable …
Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs
RM Arvola, CT Chang, JP Buytendorp… - Nucleic acids …, 2020 - academic.oup.com
Pumilio is an RNA-binding protein that represses a network of mRNAs to control embryogenesis,
stem cell fate, fertility and neurological functions in Drosophila. We sought to identify …
stem cell fate, fertility and neurological functions in Drosophila. We sought to identify …
Inhibiting transcription in cultured metazoan cells with actinomycin D to monitor mRNA turnover
WS Lai, RM Arvola, AC Goldstrohm, PJ Blackshear - Methods, 2019 - Elsevier
… René M. Arvola was supported by graduate research fellowship DGE 1256260 from the
National Science Foundation and the University of Michigan Genetics Training Program NRSA …
National Science Foundation and the University of Michigan Genetics Training Program NRSA …
[HTML][HTML] A conserved domain of Drosophila RNA-binding protein Pumilio interacts with multiple CCR4–NOT deadenylase complex subunits to repress target mRNAs
RJ Haugen, RM Arvola, RP Connacher… - Journal of Biological …, 2022 - ASBMB
Pumilio is a sequence-specific RNA-binding protein that controls development, stem cell fate,
and neurological functions in Drosophila. Pumilio represses protein expression by …
and neurological functions in Drosophila. Pumilio represses protein expression by …
Measuring Poly-Adenosine Tail Length of RNAs by High-Resolution Northern Blotting Coupled with RNase H Cleavage
RM Arvola, AC Goldstrohm - Deadenylation: Methods and Protocols, 2023 - Springer
The poly-adenosine, or poly(A) tail, plays key roles in controlling the stability and translation
of messenger RNAs in all eukaryotes, and, as such, facile assays that can measure poly(A) …
of messenger RNAs in all eukaryotes, and, as such, facile assays that can measure poly(A) …
Mammalian UPF3A and UPF3B activate NMD independently of their EJC binding
Z Yi, RM Arvola, S Myers, CN Dilsavor, RA Alhasan… - bioRxiv, 2021 - biorxiv.org
Nonsense-mediated mRNA decay (NMD) is governed by the three conserved factors - UPF1,
UPF2 and UPF3. While all three are required for NMD in yeast, UPF3B is dispensable for …
UPF2 and UPF3. While all three are required for NMD in yeast, UPF3B is dispensable for …
Messenger RNA Control by Pumilio
R Arvola - 2019 - deepblue.lib.umich.edu
Pumilio (Pum) is a sequence-specific RNA-binding protein (RBP) that recognizes Pum
Response Elements (PREs) in the 3'UTR of target mRNAs. Pum represses an extensive network …
Response Elements (PREs) in the 3'UTR of target mRNAs. Pum represses an extensive network …
[BOOK][B] Deadenylation: Methods and Protocols
E Valkov, AC Goldstrohm - 2023 - books.google.com
This volume provides new approaches and technologies into roles of poly (A) metabolism in
translation, RNA stability, and quality control of gene expression. Written in the highly …
translation, RNA stability, and quality control of gene expression. Written in the highly …