[PDF][PDF] Microglia dysfunction caused by the loss of rhoa disrupts neuronal physiology and leads to neurodegeneration

…, SH Vaz, J Magalhães, CM Silva, FI Baptista, RL Alves… - Cell Reports, 2020 - cell.com
Nervous tissue homeostasis requires the regulation of microglia activity. Using conditional
gene targeting in mice, we demonstrate that genetic ablation of the small GTPase Rhoa in …

Maternal separation effects on mother rodents' behaviour: A systematic review

RL Alves, CC Portugal, T Summavielle… - Neuroscience & …, 2020 - Elsevier
Maternal separation (MS) is a widely-used paradigm to study the effect of early-life adversity
on brain development and resilience to psychopathology. Most of the related literature …

Daily alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior

…, TO Almeida, J Tedim-Moreira, RL Alves… - Science …, 2020 - science.org
Alcohol abuse adversely affects the lives of millions of people worldwide. Deficits in synaptic
transmission and in microglial function are commonly found in human alcohol abusers and …

[HTML][HTML] Early-life stress affects drug abuse susceptibility in adolescent rat model independently of depression vulnerability

RL Alves, P Oliveira, IM Lopes, CC Portugal… - Scientific Reports, 2020 - nature.com
The development of substance abuse problems occurs due to a diverse combination of risk
factors. Among these risks, studies have reported depression and early-life stress as of …

[HTML][HTML] Maternal stress and vulnerability to depression: coping and maternal care strategies and its consequences on adolescent offspring

RL Alves, CC Portugal, IM Lopes, P Oliveira… - Translational …, 2022 - nature.com
Depressive mothers often find mother-child interaction to be challenging. Maternal stress
may further impair mother-child attachment, which may increase the risk of negative …

Postconflict Affiliation Among Bystanders in a Captive Group of Japanese Macaques (Macaca fuscata)

JR Daniel, RL Alves - International Journal of Primatology, 2015 - Springer
Social animals benefit from group living. However, competition for limited resources may lead
to agonistic conflicts. These conflicts can affect the behavior and the social relationships, …

Altered environmental perception by parental stress and depression vulnerability: impact on mothers and offspring

RL Alves, CC Portugal, IM Lopes, P Oliveira, CJ Alves… - bioRxiv, 2021 - biorxiv.org
Depressive mothers often find the mother-child interaction to be challenging. Parental stress
may further impair mother-child attachment, which may increase the risk of negative …

Alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior

…, CC Portugal, TO Almeida, J Tedim-Moreira, RL Alves… - BioRxiv, 2019 - biorxiv.org
Alcohol use adversely impacts the life of millions of people worldwide. Deficits in synaptic
transmission and in microglial function are common findings in human alcohol users and in …

ATLANTIC MAMMAL TRAITS: a data set of morphological traits of mammals in the Atlantic Forest of South America

…, A Eriksson, M Silveira, CF Santos, L Alves… - 2018 - Wiley Online Library
Measures of traits are the basis of functional biological diversity. Numerous works consider
mean species‐level measures of traits while ignoring individual variance within species. …

Molecular mechanisms regulating glia homeostasis

…, J Magalhães, CM Silva, F Baptista, RL Alves… - Free Radical Biology …, 2018 - Elsevier
Microglia are resident myeloid cells of the central nervous system that are critical for brain
functioning in health and disease. Using tissue-specific conditional gene targeting in mice, …