Genomics and epidemiology of the P. 1 SARS-CoV-2 lineage in Manaus, Brazil
…, VS Del Caro, RMF Filho, HM Dos Santos, RS Aguiar… - Science, 2021 - science.org
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …
[HTML][HTML] Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study
G Calvet, RS Aguiar, ASO Melo… - The Lancet infectious …, 2016 - thelancet.com
Background The incidence of microcephaly in Brazil in 2015 was 20 times higher than in
previous years. Congenital microcephaly is associated with genetic factors and several …
previous years. Congenital microcephaly is associated with genetic factors and several …
Evolution and epidemic spread of SARS-CoV-2 in Brazil
Brazil currently has one of the fastest-growing severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) epidemics in the world. Because of limited available data, assessments …
2 (SARS-CoV-2) epidemics in the world. Because of limited available data, assessments …
[PDF][PDF] Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings
We have detected a new variant circulating in December in Manaus, Amazonas state, north
Brazil, where very high attack rates have been estimated previously. The new lineage, …
Brazil, where very high attack rates have been estimated previously. The new lineage, …
The spectrum of neuropathological changes associated with congenital Zika virus infection
…, MB Arruda, RM Brindeiro, R Delvechio, RS Aguiar… - Acta …, 2017 - Springer
A major concern associated with ZIKV infection is the increased incidence of microcephaly
with frequent calcifications in infants born from infected mothers. To date, postmortem …
with frequent calcifications in infants born from infected mothers. To date, postmortem …
[HTML][HTML] Spatial and temporal fluctuations in COVID-19 fatality rates in Brazilian hospitals
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Gamma variant of
concern has spread rapidly across Brazil since late 2020, causing substantial infection and …
concern has spread rapidly across Brazil since late 2020, causing substantial infection and …
[HTML][HTML] Antiviral efficacy of molnupiravir versus ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19 (PLATCOV): an open-label, phase 2 …
…, M Teixeira, PJ Almeida, RS Aguiar… - The Lancet Infectious …, 2024 - thelancet.com
Background Molnupiravir and ritonavir-boosted nirmatrelvir are the two leading oral COVID-19
antiviral treatments, but their antiviral activities in patients have not been compared …
antiviral treatments, but their antiviral activities in patients have not been compared …
[HTML][HTML] Zika virus disrupts molecular fingerprinting of human neurospheres
…, G Vitória, PC Sequeira, J Sochacki, RS Aguiar… - Scientific reports, 2017 - nature.com
Zika virus (ZIKV) has been associated with microcephaly and other brain abnormalities;
however, the molecular consequences of ZIKV to human brain development are still not fully …
however, the molecular consequences of ZIKV to human brain development are still not fully …
[HTML][HTML] Nef Neutralizes the Ability of Exosomes from CD4+ T Cells to Act as Decoys during HIV-1 Infection
Nef is an HIV-1 accessory protein that promotes viral replication and pathogenesis. A key
function of Nef is to ensure sustained depletion of CD4 and MHC-I molecules in infected cells …
function of Nef is to ensure sustained depletion of CD4 and MHC-I molecules in infected cells …
Intra-host evolution during SARS-CoV-2 prolonged infection
…, RM Galliez, DS Faffe, LC Pôrto, RS Aguiar… - Virus …, 2021 - academic.oup.com
Long-term infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
represents a challenge to virus dispersion and the control of coronavirus disease 2019 (COVID-…
represents a challenge to virus dispersion and the control of coronavirus disease 2019 (COVID-…