User profiles for Rene S. Kahn
Rene Kahnicahn school of medicine at mount sinai Verified email at mssm.edu Cited by 177658 |
[HTML][HTML] The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a
collaborative network of researchers working together on a range of large-scale studies that …
collaborative network of researchers working together on a range of large-scale studies that …
Antipsychotic drug effects on brain morphology in first-episode psychosis
…, R Zipursky, T Sharma, RS Kahn… - Archives of general …, 2005 - jamanetwork.com
Background Pathomorphologic brain changes occurring as early as first-episode schizophrenia
have been extensively described. Longitudinal studies have demonstrated that these …
have been extensively described. Longitudinal studies have demonstrated that these …
Dopamine in schizophrenia: a review and reconceptualization.
KL Davis, RS Kahn, G Ko… - The American journal of …, 1991 - europepmc.org
Objective The initial hypothesis that schizophrenia is a manifestation of hyperdopaminergia
has recently been faulted. However, several new findings suggest that abnormal, although …
has recently been faulted. However, several new findings suggest that abnormal, although …
Functionally linked resting‐state networks reflect the underlying structural connectivity architecture of the human brain
During rest, multiple cortical brain regions are functionally linked forming resting‐state
networks. This high level of functional connectivity within resting‐state networks suggests the …
networks. This high level of functional connectivity within resting‐state networks suggests the …
[PDF][PDF] Modeling linkage disequilibrium increases accuracy of polygenic risk scores
Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …
become more accurate as training sample sizes increase. The standard approach for …
[HTML][HTML] Brain charts for the human lifespan
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research
and clinical studies of the human brain. However, no reference standards currently exist to …
and clinical studies of the human brain. However, no reference standards currently exist to …
Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial
RS Kahn, WW Fleischhacker, H Boter, M Davidson… - The lancet, 2008 - thelancet.com
Background Second-generation antipsychotic drugs were introduced over a decade ago for
the treatment of schizophrenia; however, their purported clinical effectiveness compared …
the treatment of schizophrenia; however, their purported clinical effectiveness compared …
Memory impairment in schizophrenia: a meta-analysis
…, R Hijman, EHF De Haan, RS Kahn - American Journal of …, 1999 - Am Psychiatric Assoc
OBJECTIVE: Memory impairment is well documented in schizophrenia. Less is known, however,
about the exact magnitude, pattern, and extent of the impairment. The effect of potential …
about the exact magnitude, pattern, and extent of the impairment. The effect of potential …
Rare coding variants in ten genes confer substantial risk for schizophrenia
…, L DeLisi, S Dodge, MA Escamilla, S Eskelinen… - Nature, 2022 - nature.com
Rare coding variation has historically provided the most direct connections between gene
function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 …
function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 …
Course and predictors of weight gain in people with first-episode psychosis treated with olanzapine or haloperidol
…, SM Strakowski, T Sharma, RS Kahn… - The British journal of …, 2005 - cambridge.org
BackgroundSubstantial weight gain is common with many atypical antipsychotics.AimsTo
evaluate the extent, time course and predictors of weight gain and its effect on study retention …
evaluate the extent, time course and predictors of weight gain and its effect on study retention …