User profiles for Rene S. Kahn

Rene Kahn

icahn school of medicine at mount sinai
Verified email at mssm.edu
Cited by 177658

[HTML][HTML] The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

…, RS Kahn, D Kasperaviciute, S Kelly, S Kim… - Brain imaging and …, 2014 - Springer
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a
collaborative network of researchers working together on a range of large-scale studies that …

Antipsychotic drug effects on brain morphology in first-episode psychosis

…, R Zipursky, T Sharma, RS Kahn… - Archives of general …, 2005 - jamanetwork.com
Background Pathomorphologic brain changes occurring as early as first-episode schizophrenia
have been extensively described. Longitudinal studies have demonstrated that these …

Dopamine in schizophrenia: a review and reconceptualization.

KL Davis, RS Kahn, G Ko… - The American journal of …, 1991 - europepmc.org
Objective The initial hypothesis that schizophrenia is a manifestation of hyperdopaminergia
has recently been faulted. However, several new findings suggest that abnormal, although …

Functionally linked resting‐state networks reflect the underlying structural connectivity architecture of the human brain

…, RCW Mandl, RS Kahn… - Human brain …, 2009 - Wiley Online Library
During rest, multiple cortical brain regions are functionally linked forming resting‐state
networks. This high level of functional connectivity within resting‐state networks suggests the …

[PDF][PDF] Modeling linkage disequilibrium increases accuracy of polygenic risk scores

…, HK Finucane, A Gusev, S Lindström, S Ripke… - The american journal of …, 2015 - cell.com
Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …

[HTML][HTML] Brain charts for the human lifespan

…, T Jia, KA Johnson, PB Jones, DT Jones, RS Kahn… - Nature, 2022 - nature.com
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research
and clinical studies of the human brain. However, no reference standards currently exist to …

Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial

RS Kahn, WW Fleischhacker, H Boter, M Davidson… - The lancet, 2008 - thelancet.com
Background Second-generation antipsychotic drugs were introduced over a decade ago for
the treatment of schizophrenia; however, their purported clinical effectiveness compared …

Memory impairment in schizophrenia: a meta-analysis

…, R Hijman, EHF De Haan, RS Kahn - American Journal of …, 1999 - Am Psychiatric Assoc
OBJECTIVE: Memory impairment is well documented in schizophrenia. Less is known, however,
about the exact magnitude, pattern, and extent of the impairment. The effect of potential …

Rare coding variants in ten genes confer substantial risk for schizophrenia

…, L DeLisi, S Dodge, MA Escamilla, S Eskelinen… - Nature, 2022 - nature.com
Rare coding variation has historically provided the most direct connections between gene
function and disease pathogenesis. By meta-analysing the whole exomes of 24,248 …

Course and predictors of weight gain in people with first-episode psychosis treated with olanzapine or haloperidol

…, SM Strakowski, T Sharma, RS Kahn… - The British journal of …, 2005 - cambridge.org
BackgroundSubstantial weight gain is common with many atypical antipsychotics.AimsTo
evaluate the extent, time course and predictors of weight gain and its effect on study retention …