Single-cell RNA sequencing (scRNA-seq) technologies are poised to reshape the current
cell-type classification system. However, a transcriptome-based single-cell atlas has not been …

Single-cell analysis is a valuable tool for dissecting cellular heterogeneity in complex systems
1 . However, a comprehensive single-cell atlas has not been achieved for humans. Here …

Individual cells are basic units of life. Despite extensive efforts to characterize the cellular
heterogeneity of different organisms, cross-species comparisons of landscape dynamics have …

Waddington’s epigenetic landscape is a metaphor frequently used to illustrate cell
differentiation. Recent advances in single-cell genomics are altering our understanding of the …

Despite extensive efforts to generate and analyze reference genomes, genetic models to
predict gene regulation and cell fate decisions are lacking for most species. Here, we …

Background Acute myeloid leukemia (AML) is a fatal hematopoietic malignancy and has a
prognosis that varies with its genetic complexity. However, there has been no appropriate …

Background Down syndrome (DS), which is characterized by various malfunctions, is the
most common chromosomal disorder. As the DS population continues to grow and most of …

… ; Renying Wang, Yunxing Wang and Lan Hu contributed to acquisition of data; Renying Wang
and Yunxing Wang … work; Renying Wang and Yunxing Wang drafted the work; Xiaoshan …

Convolutional Neural Networks (CNN) based detectors perform well in face manipulation
detection, but are still limited by redundant information. Some methods focus on blending …

Face forgery instances involving celebrities are on the rise, owing to the ease with which
their large quantity of videos may be accessible on the Internet, world leaders particularly. …