User profiles for Reshma Bhagat

Reshma Bhagat

Washington University in Saint Louis
Verified email at wustl.edu
Cited by 132

[HTML][HTML] Molecular mechanisms of zika virus pathogenesis: An update

R Bhagat, G Kaur, P Seth - Indian Journal of Medical Research, 2021 - journals.lww.com
Zika virus (ZIKV), member of the family Flaviviridae belonging to genus Flavivirus, is an
arthropod-borne virus. The ZIKV is known to cause severe congenital birth defects in neonates. …

Enhanced SMOTE algorithm for classification of imbalanced big-data using random forest

RC Bhagat, SS Patil - 2015 IEEE international advance …, 2015 - ieeexplore.ieee.org
In the era of big data, the applications generating tremendous amount of data are becoming
the main focus of attention as the wide increment of data generation and storage that has …

Zika virus E protein alters the properties of human fetal neural stem cells by modulating microRNA circuitry

R Bhagat, B Prajapati, S Narwal, N Agnihotri… - Cell Death & …, 2018 - nature.com
Zika virus (ZV) infects neural stem cells (NSCs) and causes quiescence in NSCs, reducing
the pool of brain cells, leading to microcephaly. Despite conscientious efforts, the molecular …

[HTML][HTML] Zika virus E protein modulates functions of human brain microvascular endothelial cells and astrocytes: implications on blood-brain barrier properties

G Kaur, P Pant, R Bhagat, P Seth - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
Neurotropic viruses can cross the otherwise dynamically regulated blood-brain barrier (BBB)
and affect the brain cells. Zika virus (ZIKV) is an enveloped neurotropic Flavivirus known to …

Zika virus E protein dysregulate mir-204/WNT2 signalling in human fetal neural stem cells

R Bhagat, P Rajpara, G Kaur, K Gupta, P Seth - Brain Research Bulletin, 2021 - Elsevier
Zika Virus (ZIKV) belongs to the family of flaviviruses, and is neurotrophic. It has been known
to cause severe congenital disabilities including microcephaly in neonates. The virus has a …

Identification and epigenetic analysis of divergent long non-coding RNAs in multilineage differentiation of human Neural Progenitor Cells

…, MK Sodhi, M Fatima, T Dargar, R Bhagat… - RNA biology, 2019 - Taylor & Francis
Long non-coding RNAs have emerged as an important regulatory layer in biological systems.
Of the various types of lncRNAs, one class (designated as divergent RNAs/XH), which is in …

Identification and classification of hubs in microRNA target gene networks in human neural stem/progenitor cells following Japanese encephalitis virus infection

S Mukherjee, I Akbar, R Bhagat, B Hazra… - Msphere, 2019 - Am Soc Microbiol
RNA viruses are known to modulate host microRNA (miRNA) machinery for their own benefit.
Japanese encephalitis virus (JEV), a neurotropic RNA virus, has been reported to …

Zika virus E protein alters blood-brain barrier by modulating brain microvascular endothelial cell and astrocyte functions

G Kaur, P Pant, R Bhagat, P Seth - bioRxiv, 2023 - biorxiv.org
Neurotropic viruses can cross the otherwise dynamically regulated blood-brain barrier (BBB)
and affect the brain cells. Zika virus (ZIKV) is an enveloped neurotropic Flavivirus known to …

[HTML][HTML] Long non-coding RNA SNHG8 drives stress granule formation in tauopathies

R Bhagat, MA Minaya, A Renganathan, M Mehra… - Molecular …, 2023 - nature.com
Tauopathies are a heterogenous group of neurodegenerative disorders characterized by
tau aggregation in the brain. In a subset of tauopathies, rare mutations in the MAPT gene, …

Copper dependent ERK1/2 phosphorylation is essential for the viability of neurons and not glia

K Chakraborty, S Kar, B Rai, R Bhagat, N Naskar… - Metallomics, 2022 - academic.oup.com
Intracellular copper [Cu(I)] has been hypothesized to play role in the differentiation of the
neurons. This necessitates understanding the role of Cu(I) not only in the neurons but also in …