Because of their potent adjuvanticity, ease of manipulation and simplicity of production Gram‐negative
Outer Membrane Vesicles OMVs have the potential to become a highly effective …

Background In this study, we describe the generation of a fully human monoclonal antibody (named
‘7NP2’) targeting human fibroblast activation protein (FAP), an antigen expressed in …

Human papillomaviruses (HPVs) are a large family of viruses with a capsid composed of the
L1 and L2 proteins, which bind to receptors of the basal epithelial cells and promote virus …

Human FAT1 is overexpressed on the surface of most colorectal cancers (CRCs) and in
particular a 25 amino acid sequence (D8) present in one of the 34 cadherin extracellular repeats …

IL15 is an immunostimulatory cytokine that holds promises for cancer therapy, but its
performance (alone or as partner for fusion proteins) has often been limited by suboptimal …

… Corbellari, Riccardo a,,b,,* ; Nadal, Lisa a,,b,,* ; Villa, Alessandra b ; Neri, Dario c ; De Luca,
Roberto … * Riccardo Corbellari and Lisa Nadal contributed equally to the writing of this article. …

The targeted delivery of interleukin-2 to the tumor is gaining attention as an avenue to
potentiate the action of T and NK cells at the site of disease. We have previously described the …

Simple Summary In situ vaccination (ISV) envisages the intratumoral injection of
immunostimulatory molecules, which inflame the tumor and induce anti-tumor immune responses. …

The vaccination campaign against SARS-CoV-2 relies on the world-wide availability of
effective vaccines, with a potential need of 20 billion vaccine doses to fully vaccinate the world …

Antibody-based delivery of bioactive molecules represents a promising strategy for the
improvement of cancer immunotherapy. Here, we describe the generation and characterization of …