Potent inhibitors of enzymes catalyzing reactions in the de novo pathways for biosynthesis
of purine and pyrimidine nucleotides are synthetic or natural-product analogues of pathway …

Different leukemias express on their plasma membranes particular subsets of the 247 defined
cluster of differentiation (CD) antigens, which may resemble those of precursor cells along …

The classification of colorectal cancers (CRC) is currently based largely on histologically
determined tumour characteristics, such as differentiation status and tumour stage, ie, depth of …

Protein arrays are now an attractive proposition as they can measure a diverse range of
protein interactions not possible with traditional DNA arrays. Antibody arrays are a specific …

This is a study of the relationship between "calling" and "career" in the lives of American
clergy. Data were collected through a series of intensive interviews with ministers and priests …

Extracellular vesicles (EV) are membranous particles (30–1,000 nm in diameter) secreted by
cells. Important biological functions have been attributed to 2 subsets of EV, the exosomes (…

Extracellular vesicles (EVs) play key roles in glioblastoma (GBM) biology and represent
novel sources of biomarkers that are detectable in the peripheral circulation. Despite this …

We have previously described a microarray of cluster of differentiation (CD) antibodies that
enables concurrent determination of more than 60 CD antigens on leukocytes. This …

Protein kinases play key roles in oncogenic signaling and are a major focus in the
development of targeted cancer therapies. Imatinib, a BCR-Abl tyrosine kinase inhibitor, is a …

The need to provide alternative and exciting community service-learning experiences with
university students has been a challenge to institutions of higher education. One institution …