A systematic genome-wide analysis of zebrafish protein-coding gene function
Since the publication of the human reference genome, the identities of specific genes associated
with human diseases are being discovered at a rapid rate. A central problem is that the …
with human diseases are being discovered at a rapid rate. A central problem is that the …
[HTML][HTML] How global is the global biodiversity information facility?
There is a concerted global effort to digitize biodiversity occurrence data from herbarium and
museum collections that together offer an unparalleled archive of life on Earth over the past …
museum collections that together offer an unparalleled archive of life on Earth over the past …
Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor
…, PS Margolis, C Wu, ZJ Ni, J Trias, RJ White… - Biochemistry, 2000 - ACS Publications
Peptide deformylase (PDF) is essential in prokaryotes and absent in mammalian cells, thus
making it an attractive target for the discovery of novel antibiotics. We have identified …
making it an attractive target for the discovery of novel antibiotics. We have identified …
A high-resolution mRNA expression time course of embryonic development in zebrafish
10.7554/eLife.30860.001 We have produced an mRNA expression time course of zebrafish
development across 18 time points from 1 cell to 5 days post-fertilisation sampling individual …
development across 18 time points from 1 cell to 5 days post-fertilisation sampling individual …
Localization and composition of lipids in neonatal mouse stratum granulosum and stratum corneum
…, P Fritsch, J Goerke, GM Gray, RJ White - Journal of Investigative …, 1979 - Elsevier
… J Lipid Res 16:441-447, 1975 15. Gray GM, White RJ: Glycosphingolipids and ceramides
in human and pig epidermis. J Invest Dermatol 70:336- 34 1, 1978 16. Elias PM, Fritsch P, …
in human and pig epidermis. J Invest Dermatol 70:336- 34 1, 1978 16. Elias PM, Fritsch P, …
Novel oxazolidinone–quinolone hybrid antimicrobials
…, GE Zurenko, CN Parker, JM Evans, RJ White… - Bioorganic & medicinal …, 2003 - Elsevier
Antimicrobial compounds incorporating oxazolidinone and quinolone pharmacophore
substructures have been synthesized and evaluated. Representative analogues 2, 5, and 6 …
substructures have been synthesized and evaluated. Representative analogues 2, 5, and 6 …
The evolution of peptide deformylase as a target: contribution of biochemistry, genetics and genomics
Z Yuan, RJ White - Biochemical pharmacology, 2006 - Elsevier
Although peptide deformylase (PDF, EC 3.5.1.27) was first described in 1968, the instability
of enzyme preparations prevented it from being seriously considered as a target until this …
of enzyme preparations prevented it from being seriously considered as a target until this …
Detection of gilvocarcin antitumor complex by a biochemical induction assay (BIA)
…, U WEISS, RM STROSHANE, RJ WHITE… - The Journal of …, 1982 - jstage.jst.go.jp
We are currently investigating the applicability of a biochemical version of the prophage
induction assay (BIA) 1), a test for agents interacting with DNA, as a potential prescreen for new …
induction assay (BIA) 1), a test for agents interacting with DNA, as a potential prescreen for new …
[HTML][HTML] Neoadjuvant PD-1 blockade in resectable lung cancer
Background Antibodies that block programmed death 1 (PD-1) protein improve survival in
patients with advanced non–small-cell lung cancer (NSCLC) but have not been tested in …
patients with advanced non–small-cell lung cancer (NSCLC) but have not been tested in …
Molecular paleohydrology: interpreting the hydrogen-isotopic composition of lipid biomarkers from photosynthesizing organisms
…, HL Schmidt, AL Sessions, JWC White… - Annual Review of …, 2012 - annualreviews.org
Hydrogen-isotopic abundances of lipid biomarkers are emerging as important proxies in the
study of ancient environments and ecosystems. A decade ago, pioneering studies made …
study of ancient environments and ecosystems. A decade ago, pioneering studies made …