User profiles for Richard Sam

Richard Sam

MD/PhD Student, NYU Grossman School of Medicine
Verified email at nyulangone.org
Cited by 222

[HTML][HTML] Small Molecule Chaperones for the Treatment of Gaucher Disease and GBA1-Associated Parkinson Disease

TU Han, R Sam, E Sidransky - Frontiers in cell and developmental …, 2020 - frontiersin.org
Parkinson disease, the second most common movement disorder, is a complex neurodegenerative
disorder hallmarked by the accumulation of alpha-synuclein, a neural-specific small …

Current and emerging pharmacotherapy for Gaucher disease in pediatric populations

R Sam, E Ryan, E Daykin… - Expert opinion on …, 2021 - Taylor & Francis
Introduction The past decades have witnessed a remarkable improvement in the health of
patients with Gaucher disease, the inherited deficiency of the lysosomal enzyme …

[PDF][PDF] A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation

Z Liu, H Nailwal, J Rector, MM Rahman, R Sam… - Immunity, 2021 - cell.com
The vaccine strain against smallpox, vaccinia virus (VACV), is highly immunogenic yet
causes relatively benign disease. These attributes are believed to be caused by gene loss in …

Glucocerebrosidase as a therapeutic target for Parkinson's disease

Y Chen, R Sam, P Sharma, L Chen, J Do… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: The association between Gaucher disease, caused by the inherited deficiency
of glucocerebrosidase, and Parkinson’s disease was first recognized in the clinic, noting that …

Agritourism, farm visit, or...? A branding assessment for recreation on farms

…, S Xu, C Gil-Arroyo, SR Rich - Journal of travel …, 2016 - journals.sagepub.com
The demand and offer of recreational activities on farms has increased over the last decades
and promises increased growth in the future because of the benefits it brings to farmers and …

The NCI genomic data commons

…, JJ Porter, R Powell, K Rademacher, CP Reid, S Rich… - Nature …, 2021 - nature.com
The National Cancer Institute (NCI) Genomic Data Commons (GDC) contains more than 2.9
petabytes of genomic and associated clinical data from more than 60 NCI-funded and other …

Prophase I arrest of mouse oocytes mediated by natriuretic peptide precursor C requires GJA1 (connexin-43) and GJA4 (connexin-37) gap junctions in the antral …

S Richard, JM Baltz - Biology of reproduction, 2014 - academic.oup.com
Fully grown germinal vesicle stage mouse oocytes remain arrested in meiotic prophase I
until ovulation. This arrest is maintained by cGMP produced in cumulus granulosa cells …

Engineering geometrical 3-dimensional untethered in vitro neural tissue mimic

…, KP Ramos-Cruz, R Sam… - Proceedings of the …, 2019 - National Acad Sciences
Formation of tissue models in 3 dimensions is more effective in recapitulating structure and
function compared to their 2-dimensional (2D) counterparts. Formation of 3D engineered …

Optical excitation and detection of neuronal activity

C Hu, R Sam, M Shan, V Nastasa, M Wang… - Journal of …, 2019 - Wiley Online Library
Optogenetics has emerged as an exciting tool for manipulating neural activity, which in turn,
can modulate behavior in live organisms. However, detecting the response to the optical …

Meeting extension programming needs with technology: A case study of agritourism webinars

SR Rich, S Komar, B Schilling… - The Journal of …, 2011 - tigerprints.clemson.edu
As clientele needs diversify, Extension educators are examining new technologies, including
online tools, to deliver educational programming and resources. Using agritourism as the …