User profiles for Richard Steinman

Richard Steinman

Verified email at pitt.edu
Cited by 3077

Induction of p21 (WAF-1/CIP1) during differentiation.

RA Steinman, B Hoffman, A Iro, C Guillouf… - Oncogene, 1994 - europepmc.org
The recently cloned protein, p21 (WAF1/CIP1) is a downstream effector of p53, and mediates
growth arrest by inhibiting the action of G1 cyclin-dependent kinases. Since cellular …

Frequency domain measures of heart period variability and mortality after myocardial infarction.

JT Bigger Jr, JL Fleiss, RC Steinman, LM Rolnitzky… - Circulation, 1992 - Am Heart Assoc
BACKGROUND We studied 715 patients 2 weeks after myocardial infarction to establish the
associations between six frequency domain measures of heart period variability (HPV) and …

The ability of several short-term measures of RR variability to predict mortality after myocardial infarction.

JT Bigger, JL Fleiss, LM Rolnitzky, RC Steinman - Circulation, 1993 - Am Heart Assoc
BACKGROUND We studied 715 patients 2 weeks after myocardial infarction to test the
hypothesis that short-term power spectral measures of RR variability (calculated from 2 to 15 …

RR variability in healthy, middle-aged persons compared with patients with chronic coronary heart disease or recent acute myocardial infarction

JT Bigger Jr, JL Fleiss, RC Steinman, LM Rolnitzky… - Circulation, 1995 - Am Heart Assoc
Background The purpose of this investigation was to establish normal values of RR variability
for middle-aged persons and compare them with values found in patients early and late …

Components of heart rate variability measured during healing of acute myocardial infarction

…, JL Fleiss, LM Rolnitzky, RC Steinman… - The American journal of …, 1988 - Elsevier
A high degree of heart rate (HR) variability is found in persons with normal hearts, whereas
low HR variability can be found in patients with severe coronary artery disease, congestive …

Correlations among time and frequency domain measures of heart period variability two weeks after acute myocardial infarction

JT Bigger Jr, JL Fleiss, RC Steinman… - The American journal of …, 1992 - Elsevier
Seven hundred fifteen participants from a multicenter natural history study of acute myocardial
infarction were studied (1) to determine the correlations among time and frequency …

Stability over time of variables measuring heart rate variability in normal subjects

…, MK Chung, JR Cook, LM Rolnitzky, R Steinman… - The American journal of …, 1991 - Elsevier
Both time and frequency domain measures of heart rate (HR) variability have been used to
assess autonomic tone in a variety of clinical conditions. Few studies in normal subjects have …

Power law behavior of RR-interval variability in healthy middle-aged persons, patients with recent acute myocardial infarction, and patients with heart transplants

JT Bigger Jr, RC Steinman, LM Rolnitzky, JL Fleiss… - Circulation, 1996 - Am Heart Assoc
Background The purposes of the present study were (1) to establish normal values for the
regression of log(power) on log(frequency) for RR-interval fluctuations in healthy middle-aged …

[HTML][HTML] Frequency domain measures of heart period variability to assess risk late after myocardial infarction

…, JL Fleiss, LM Rolnitzky, RC Steinman - Journal of the American …, 1993 - Elsevier
Objectives. To determine whether spectral measures of heart period (RR) variability predict
death when measured late after infarction, we studied patients in the Cardiac Arrhythmia …

[HTML][HTML] Comparison of 24-hour parasympathetic activity in endurance-trained and untrained young men

RL Goldsmith, JT Bigger Jr, RC Steinman… - Journal of the American …, 1992 - Elsevier
Objectives. This study compares 24-h parasympathetic activity in aerobically trained and
untrained healthy young men. Background. Higher values of parasympathetic nervous system …