Background The number of prokaryotic genome sequences becoming available is growing
steadily and is growing faster than our ability to accurately annotate them. Description We …

In 2004, the SEED ( http://pubseed.theseed.org/ ) was created to provide consistent and
accurate genome annotations across thousands of genomes and as a platform for discovering …

Background Random community genomes (metagenomes) are now commonly used to
study microbes in different environments. Over the past few years, the major challenge …

The Pathosystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics
Resource Center ( https://www.patricbrc.org ). Recent changes to PATRIC include a redesign of …

The Pathosystems Resource Integration Center (PATRIC) is the all-bacterial Bioinformatics
Resource Center (BRC) ( http://www.patricbrc.org ). A joint effort by two of the original …

The emergence and spread of antimicrobial resistance (AMR) mechanisms in bacterial
pathogens, coupled with the dwindling number of effective antibiotics, has created a global …

Our growing awareness of the microbial world’s importance and diversity contrasts starkly
with our limited understanding of its fundamental structure. Despite recent advances in DNA …

The RAST (Rapid Annotation using Subsystem Technology) annotation engine was built in
2008 to annotate bacterial and archaeal genomes. It works by offering a standard software …

The release of the 1000 th complete microbial genome will occur in the next two to three
years. In anticipation of this milestone, the Fellowship for Interpretation of Genomes (FIG) …

The National Institute of Allergy and Infectious Diseases (NIAID) established the Bioinformatics
Resource Center (BRC) program to assist researchers with analyzing the growing body …