[HTML][HTML] Clustering by phenotype and genome-wide association study in autism

…, S Ogishima, G Tamiya, M Ueki, R Sakurai… - Translational …, 2020 - nature.com
Autism spectrum disorder (ASD) has phenotypically and genetically heterogeneous characteristics.
A simulation study demonstrated that attempts to categorize patients with a complex …

Children's eating attitudes test: reliability and validation in Japanese adolescents

H Chiba, S Nagamitsu, R Sakurai, T Mukai, H Shintou… - Eating behaviors, 2016 - Elsevier
Eating disorders (ED) are serious psychosomatic disorders that commonly occur in girls
during adolescence. An increase in earlier onset ED has recently been suggested. Therefore, …

[HTML][HTML] Development of a prognostic prediction support system for cervical intraepithelial neoplasia using artificial intelligence-based diagnosis

T Takahashi, H Matsuoka, R Sakurai… - Journal of …, 2022 - ncbi.nlm.nih.gov
Objective Human papillomavirus subtypes are predictive indicators of cervical intraepithelial
neoplasia (CIN) progression. While colposcopy is also an essential part of cervical cancer …

Outlier detection for questionnaire data in biobanks

R Sakurai, M Ueki, S Makino, A Hozawa… - International journal …, 2019 - academic.oup.com
Background Biobanks increasingly collect, process and store omics with more conventional
epidemiologic information necessitating considerable effort in data cleaning. An efficient …

[HTML][HTML] Altered SPECT 123I-iomazenil Binding in the Cingulate Cortex of Children with Anorexia Nervosa

S Nagamitsu, R Sakurai, M Matsuoka, H Chiba… - Frontiers in …, 2016 - frontiersin.org
Several lines of evidence suggest that anxiety plays a key role in the development and
maintenance of anorexia nervosa (AN) in children. The purpose of this study was to examine …

Goodness-of-fit test for the parametric proportional hazard regression model with interval-censored data

R Sakurai, S Hattori - Biostatistics & Epidemiology, 2018 - Taylor & Francis
Interval-censored data are common in medical research. Fully parametric models provide
simple and efficient inference for the estimation of survival functions using interval-censored …

Holonomic Decent Minimization Method for Restricted Maximum Likelihood Estimation

R Sakurai, T Sakata - arXiv preprint arXiv:1309.1246, 2013 - arxiv.org
Recently, the school of Takemura and Takayama have developed a quite interesting minimization
method called holonomic gradient descent method (HGD). It works by a mixed use of …

SELECTING BETTER GENERIC DRUGS

M Hayakawa, T Yanagawa, Y Jiang, R Sakurai - 2014 - catalog.lib.kyushu-u.ac.jp
Often, more than twenty generic (GE) drugs are developed for one brand name (BN) drug.
Each GE drug has passed the trial of bio-equivalence to the BN drug, and its characteristics (…

Children's Eating Attitudes Test-26; Japanese Version

H Chiba, S Nagamitsu, R Sakurai, T Mukai, H Shintou… - Eating Behaviors - psycnet.apa.org
The Children's Eating Attitudes Test-26; Japanese Version (ChEAT-26; Chiba et al., 2016)
was developed and translated from the original ChEAT-26 (Maloney et al., 1989), a self-…

Formal proof of the requirement of MESP1 and MESP2 in mesoderm specification and their transcriptional control via specific enhancers in mice

R Ajima, Y Sakakibara, N Sakurai-Yamatani… - …, 2021 - journals.biologists.com
MESP1 and MESP2 are transcriptional factors involved in mesoderm specification, somite
boundary formation and somite polarity regulation. However, Mesp quadruple mutant …