User profiles for Rifat Hamoudi

Rifat Hamoudi

Professor in Molecular, Cellular and Computational Medicine, University of Sharjah, UAE
Verified email at sharjah.ac.ae
Cited by 20282

Identification of the breast cancer susceptibility gene BRCA2

…, C Gumbs, G Micklem, R Barfoot, R Hamoudi… - Nature, 1995 - nature.com
IN Western Europe and the United States approximately 1 in 12 women develop breast cancer.
A small proportion of breast cancer cases, in particular those arising at a young age, are …

[HTML][HTML] Bcl10 is involved in t (1; 14)(p22; q32) of MALT B cell lymphoma and mutated in multiple tumor types

…, I Wlodarska, L Pan, T Crook, R Hamoudi… - Cell, 1999 - cell.com
MALT B cell lymphomas with t(1;14)(p22;q32) showed a recurrent breakpoint upstream of
the promoter of a novel gene, Bcl10. Bcl10 is a cellular homolog of the equine herpesvirus-2 …

Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone

…, O Myklebost, D Baumhoer, G Jundt, R Hamoudi… - Nature …, 2013 - nature.com
It is recognized that some mutated cancer genes contribute to the development of many
cancer types, whereas others are cancer type specific. For genes that are mutated in multiple …

T (11; 18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication

…, PL Zinzani, A Neubauer, M Stolte, RA Hamoudi… - Gastroenterology, 2002 - Elsevier
BACKGROUND & AIMS: Eradication of Helicobacter pylori leads to cure of gastric mucosa-associated
lymphoid tissue (MALT) lymphoma in 75% of localized cases. However, …

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation

…, PA Harrington, M Chiano, S Seal, R Hamoudi… - Nature …, 1995 - nature.com
Mutations in the BRCA1 gene, discovered in 1994, are associated with an 80–90% lifetime
risk of breast cancer. We have analysed 60 families with a history of breast and/or ovarian …

Resistance of t (11; 18) positive gastric mucosa-associated lymphoid tissue lymphoma to Helicobacter pylori eradication therapy

…, H Ye, T Molina, Y Bouhnik, RA Hamoudi… - The Lancet, 2001 - thelancet.com
20–30% of gastric mucosa-associated lymphoid tissue (MALT) lymphoma associated with
Helicobacter pylori do not regress after antibiotic therapy. Regression can be assessed only …

High incidence of Kaposi sarcoma–associated herpesvirus–related non-Hodgkin lymphoma in patients with HIV infection and multicentric Castleman disease

…, MQ Du, N Dupin, TC Diss, R Hamoudi… - Blood, The Journal …, 2002 - ashpublications.org
Multicentric Castleman disease (MCD) is a distinct type of lymphoproliferative disorder
associated with inflammatory symptoms and interleukin 6 (IL-6) dysregulation. In the context of …

Kaposi sarcoma–associated herpesvirus infects monotypic (IgMλ) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders

…, H Liu, TC Diss, H Ye, RA Hamoudi… - Blood, The Journal …, 2001 - ashpublications.org
In a previous study, it was shown that the Kaposi sarcoma–associated herpesvirus (KSHV)
was specifically associated with monotypic (IgMλ) plasmablasts in multicentric Castleman …

[PDF][PDF] Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene

SM Edwards, Z Kote-Jarai, J Meitz, R Hamoudi… - The American Journal of …, 2003 - cell.com
Studies of families with breast cancer have indicated that male carriers of BRCA2 mutations
are at increased risk of prostate cancer, particularly at an early age. To evaluate the …

The t(X;1)(p11.2;q21.2) Translocation in Papillary Renal Cell Carcinoma Fuses a Novel Gene PRCC to the TFE3 Transcription Factor Gene

SK Sidhar, J Clark, S Gill, R Hamoudi… - Human molecular …, 1996 - academic.oup.com
The specific chromosomal translocation t(X;1)(p11.2; q21.2) has been observed in human
papillary renal cell carcinomas. In this study we demonstrated that this translocation results in …