Searches for the genetic underpinnings of uniquely human traits have focused on human-specific
divergence in conserved genomic regions, which reflects adaptive modifications of …

TGFβ has both tumor suppressive and tumor promoting effects in colon cancer. Also, TGFβ
can affect the extent and composition of inflammatory cells present in tumors, contextually …

Each year, >180,000 infants become infected via mother-to-child transmission (MTCT) of HIV
despite the availability of effective maternal antiretroviral treatments, underlining the need …

Interactions between innate antiviral factors at mucosal surfaces and HIV-1 virions
contribute to the natural inefficiency of HIV-1 transmission and are a platform to inform the …

Pancreatic cancer is characterized by a pronounced fibro-inflammatory reaction that has
been shown to contribute to cancer progression. Previous reports have demonstrated that …

Many existing software libraries for genomics require researchers to pick between competing
considerations: the performance of compiled languages and the accessibility of interpreted …

Immunodominant and highly conserved flavivirus envelope proteins can trigger cross-reactive
IgG antibodies against related flaviviruses, which shapes subsequent protection or …

Global elimination of pediatric human immunodeficiency virus (HIV) infections will require
the development of novel immune-based approaches, and understanding infant immunity to …

Breast milk HIV-1 transmission is currently the predominant contributor to pediatric HIV
infections. Yet, only ~10% of breastfeeding infants born to untreated HIV-infected mothers …

Lactoferrin supplementation may help prevent infections in preterm infants, but the efficacy
has varied with different doses and products. We assessed the absorption and excretion of …