Concentric left ventricular (LV) remodeling is associated with adverse cardiovascular events
and is frequently observed in patients with type 2 diabetes mellitus (T2DM). Despite this, the …

Background : Type 2 diabetes (T2D) and obesity are associated with nonalcoholic fatty liver
disease, cardiomyopathy, and cardiovascular mortality. Both show stronger links between …

Aims Patients with type 2 diabetes mellitus (T2DM) are known to have impaired resting
myocardial energetics and impaired myocardial perfusion reserve, even in the absence of …

Aims Myocardial fibrosis as detected by late gadolinium enhancement (LGE) on cardiac
magnetic resonance (CMR) is a powerful prognostic marker in hypertrophic cardiomyopathy (…

Background : Myocardial disarray is a likely focus for fatal arrhythmia in hypertrophic
cardiomyopathy (HCM). This microstructural abnormality can be inferred by mapping the …

Aims: Ventricular arrhythmia triggers sudden cardiac death (SCD) in hypertrophic cardiomyopathy
(HCM), yet electrophysiological biomarkers are not used for risk stratification. Our aim …

Background Type 2 diabetes mellitus (T2DM) is associated with coronary microvascular
dysfunction in the absence of obstructive coronary artery disease (CAD). Cardiovascular …

Background: Lone atrial fibrillation (AF) may reflect a subclinical cardiomyopathy that persists
after sinus rhythm (SR) restoration, providing a substrate for AF recurrence. To test this …

Background Heart failure (HF) is characterized by altered myocardial substrate metabolism
which can lead to myocardial triglyceride accumulation (steatosis) and lipotoxicity. However …

Aims Patient-to-patient anatomical differences are an important source of variability in the
electrocardiogram, and they may compromise the identification of pathological …