High-resolution genetic mapping using the Mouse Diversity outbred population
The JAX Diversity Outbred population is a new mouse resource derived from partially
inbred Collaborative Cross strains and maintained by randomized outcrossing. As such, it …
inbred Collaborative Cross strains and maintained by randomized outcrossing. As such, it …
Quantitative trait locus mapping methods for diversity outbred mice
Genetic mapping studies in the mouse and other model organisms are used to search for
genes underlying complex phenotypes. Traditional genetic mapping studies that employ single…
genes underlying complex phenotypes. Traditional genetic mapping studies that employ single…
[HTML][HTML] TraitCapture: genomic and environment modelling of plant phenomic data
… RiyanCheng 1 5 … Cheng, M. Abney, AA Palmer, AD Skol … Cheng, J. Borevitz, RW Doerge …
Variation in leaf respiration rates at night correlates with carbohydrate and amino acid supply
BM O'Leary, CP Lee, OK Atkin, R Cheng… - Plant …, 2017 - academic.oup.com
Plant respiration can theoretically be fueled by and dependent upon an array of central
metabolism components; however, which ones are responsible for the quantitative variation …
metabolism components; however, which ones are responsible for the quantitative variation …
Genome-wide association studies and the problem of relatedness among advanced intercross lines and other highly recombinant populations
R Cheng, JE Lim, KE Samocha, G Sokoloff, M Abney… - Genetics, 2010 - academic.oup.com
Abstract Model organisms offer many advantages for the genetic analysis of complex traits.
However, identification of specific genes is often hampered by a lack of recombination …
However, identification of specific genes is often hampered by a lack of recombination …
[PDF][PDF] Genome-wide association studies of human and rat BMI converge on synapse, epigenome, and hormone signaling networks
A vexing observation in genome-wide association studies (GWASs) is that parallel analyses
in different species may not identify orthologous genes. Here, we demonstrate that cross-…
in different species may not identify orthologous genes. Here, we demonstrate that cross-…
[HTML][HTML] Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity
…, SL Kirkpatrick, JE Lim, G Sokoloff, R Cheng… - PLoS …, 2015 - journals.plos.org
Psychostimulant addiction is a heritable substance use disorder; however its genetic basis
is almost entirely unknown. Quantitative trait locus (QTL) mapping in mice offers a …
is almost entirely unknown. Quantitative trait locus (QTL) mapping in mice offers a …
[HTML][HTML] Using phenomic analysis of photosynthetic function for abiotic stress response gene discovery
Monitoring the photosynthetic performance of plants is a major key to understanding how
plants adapt to their growth conditions. Stress tolerance traits have a high genetic complexity …
plants adapt to their growth conditions. Stress tolerance traits have a high genetic complexity …
Genome‐wide association study in 3,173 outbred rats identifies multiple loci for body weight, adiposity, and fasting glucose
Objective Obesity is influenced by genetic and environmental factors. Despite the success
of human genome‐wide association studies, the specific genes that confer obesity remain …
of human genome‐wide association studies, the specific genes that confer obesity remain …
Genetic Variation for Life History Sensitivity to Seasonal Warming in Arabidopsis thaliana
Climate change has altered life history events in many plant species; however, little is known
about genetic variation underlying seasonal thermal response. In this study, we simulated …
about genetic variation underlying seasonal thermal response. In this study, we simulated …