Ecdysteroids regulate yolk protein uptake by Drosophila melanogaster oocytes
DS Richard, NL Watkins, RB Serafin… - Journal of insect …, 1998 - Elsevier
Juvenile hormones (JHs) are thought to drive the regulation of yolk protein uptake by ovaries
in Drosophila melanogaster. However, the level of JH production in a mutant stock (ap 56f ) …
in Drosophila melanogaster. However, the level of JH production in a mutant stock (ap 56f ) …
A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues
Light-sheet microscopy has emerged as the preferred means for high-throughput volumetric
imaging of cleared tissues. However, there is a need for a flexible system that can address …
imaging of cleared tissues. However, there is a need for a flexible system that can address …
Direct three-dimensional segmentation of prostate glands with nnU-Net
Significance In recent years, we and others have developed non-destructive methods to
obtain three-dimensional (3D) pathology datasets of clinical biopsies and surgical specimens. …
obtain three-dimensional (3D) pathology datasets of clinical biopsies and surgical specimens. …
An end-to-end workflow for nondestructive 3D pathology
…, E Baraznenok, L Lan, C Poudel, G Gao, RB Serafin… - Nature …, 2024 - nature.com
Recent advances in 3D pathology offer the ability to image orders of magnitude more tissue
than conventional pathology methods while also providing a volumetric context that is not …
than conventional pathology methods while also providing a volumetric context that is not …
Non-Orthogonal Dual-Objective (NODO) Open-Top Light-Sheet (OTLS) Microscopy for 3D Pathology of Cleared Clinical Specimens
… Barner2, Robert B. Serafin2, Jonathan TC Liu1,2,3 … b) Axial sweeping principle, where
the beam waist of a moderateNA light sheet with short Rayleigh range (ZR) is scanned in …
the beam waist of a moderateNA light sheet with short Rayleigh range (ZR) is scanned in …
3D pathology of cleared clinical specimens using an optimized nonorthogonal dual-objective (NODO) open-top light-sheet (OTLS) microscope (Conference …
Open-Top Light-Sheet (OTLS) microscopy is an emerging technique for cleared-tissue imaging
that alleviates many of the physical constraints on sample size and geometry associated …
that alleviates many of the physical constraints on sample size and geometry associated …
Analysis of 3D nuclear spatial architecture for prostate cancer risk stratification (Conference Presentation)
RB Serafin, V Roybal, C Koyuncu… - … and Processing XXX, 2023 - spiedigitallibrary.org
Non-destructive 3D microscopy enables the accurate characterization of diagnostically and
prognostically significant microstructures in clinical specimens with significantly increased …
prognostically significant microstructures in clinical specimens with significantly increased …
A comprehensive workflow to generate 3D pathology datasets for large-scale clinical studies
…, L Lan, G Gao, RB Serafin… - … and Spectroscopy V, 2024 - spiedigitallibrary.org
Conventional pathology workflows rely on two-dimensional, slide-based analysis of thin
tissue sections. This approach comes with several key limitations including limited sampling, …
tissue sections. This approach comes with several key limitations including limited sampling, …
Effects of polycyclic aromatic hydrocarbons and abiotic stressors on Fundulus grandis cardiac transcriptomics
Following the 2010 Deepwater Horizon oil spill, extensive research has been conducted on
the toxicity of oil and polycyclic aromatic hydrocarbons (PAHs) in the aquatic environment. …
the toxicity of oil and polycyclic aromatic hydrocarbons (PAHs) in the aquatic environment. …
The influence of hypoxia on the cardiac transcriptomes of two estuarine species-C. variegatus and F. grandis
Increased nutrient loading has led to eutrophication of coastal shelf waters which has
resulted in increased prevalence of persistent hypoxic zones – areas in which the dissolved …
resulted in increased prevalence of persistent hypoxic zones – areas in which the dissolved …