Juvenile hormones (JHs) are thought to drive the regulation of yolk protein uptake by ovaries
in Drosophila melanogaster. However, the level of JH production in a mutant stock (ap 56f ) …

Light-sheet microscopy has emerged as the preferred means for high-throughput volumetric
imaging of cleared tissues. However, there is a need for a flexible system that can address …

Significance In recent years, we and others have developed non-destructive methods to
obtain three-dimensional (3D) pathology datasets of clinical biopsies and surgical specimens. …

Recent advances in 3D pathology offer the ability to image orders of magnitude more tissue
than conventional pathology methods while also providing a volumetric context that is not …

… Barner2, Robert B. Serafin2, Jonathan TC Liu1,2,3 … b) Axial sweeping principle, where
the beam waist of a moderateNA light sheet with short Rayleigh range (ZR) is scanned in …

Open-Top Light-Sheet (OTLS) microscopy is an emerging technique for cleared-tissue imaging
that alleviates many of the physical constraints on sample size and geometry associated …

Non-destructive 3D microscopy enables the accurate characterization of diagnostically and
prognostically significant microstructures in clinical specimens with significantly increased …

Conventional pathology workflows rely on two-dimensional, slide-based analysis of thin
tissue sections. This approach comes with several key limitations including limited sampling, …

Following the 2010 Deepwater Horizon oil spill, extensive research has been conducted on
the toxicity of oil and polycyclic aromatic hydrocarbons (PAHs) in the aquatic environment. …

Increased nutrient loading has led to eutrophication of coastal shelf waters which has
resulted in increased prevalence of persistent hypoxic zones – areas in which the dissolved …