The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA
Helicobacter pylori infects half of the world's population, and strains that encode the cag type
IV secretion system for injection of the oncoprotein CagA into host gastric epithelial cells …
IV secretion system for injection of the oncoprotein CagA into host gastric epithelial cells …
[PDF][PDF] IL-1 family cytokines use distinct molecular mechanisms to signal through their shared co-receptor
Within the interleukin 1 (IL-1) cytokine family, IL-1 receptor accessory protein (IL-1RAcP) is
the co-receptor for eight receptor-cytokine pairs, including those involving cytokines IL-1β and …
the co-receptor for eight receptor-cytokine pairs, including those involving cytokines IL-1β and …
Diverse oligomeric states of CEACAM IgV domains
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) comprise a large
family of cell surface adhesion molecules that bind to themselves and other family members to …
family of cell surface adhesion molecules that bind to themselves and other family members to …
Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2
Immunoglobulin G (IgG) glycosylation critically modulates antibody effector functions.
Streptococcus pyogenes secretes a unique endo-β-N-acetylglucosaminidase, EndoS2, which …
Streptococcus pyogenes secretes a unique endo-β-N-acetylglucosaminidase, EndoS2, which …
[HTML][HTML] Molecular basis of selective cytokine signaling inhibition by antibodies targeting a shared receptor
…, K Sjöström, S Günther, R Beadenkopf… - Frontiers in …, 2021 - frontiersin.org
Interleukin-1 (IL-1) family cytokines are potent mediators of inflammation, acting to coordinate
local and systemic immune responses to a wide range of stimuli. Aberrant signaling by IL-1 …
local and systemic immune responses to a wide range of stimuli. Aberrant signaling by IL-1 …
[HTML][HTML] Integrin engagement by the helical RGD motif of the Helicobacter pylori CagL protein is regulated by pH-induced displacement of a neighboring helix
DA Bonsor, KT Pham, R Beadenkopf… - Journal of Biological …, 2015 - ASBMB
Arginine-aspartate-glycine (RGD) motifs are recognized by integrins to bridge cells to one
another and the extracellular matrix. RGD motifs typically reside in exposed loop …
another and the extracellular matrix. RGD motifs typically reside in exposed loop …
Select targeting of intracellular Toll-interleukin-1 receptor resistance domains for protection against influenza-induced disease
…, LJ Brown, JCG Blanco, R Beadenkopf… - Innate …, 2020 - journals.sagepub.com
TLRs are a family of PRRs that respond to PAMPs or host-derived Danger-Associated
Molecular Patterns (DAMPs) to initiate host inflammation and immune responses. TLR …
Molecular Patterns (DAMPs) to initiate host inflammation and immune responses. TLR …
PC-11 Select targeting of diffuse large B-cell lymphomas using MyD88 small molecule inhibitors
…, M Sherman, J Montague, R Beadenkopf… - JAIDS Journal of …, 2019 - journals.lww.com
… Robert Gallo’s group at the NCI in 1980. Independently, a Japanese group led by Dr. Yorio
… Institute of Child Health and Human Development, US Robert Gallo, MD, Director, Institute of …
… Institute of Child Health and Human Development, US Robert Gallo, MD, Director, Institute of …
G-104 The Helicobacter pylori adhesin protein HopQ exploits the dimer interface of human CEACAMs for oncoprotein translocation
…, J Wang, D Deredge, R Beadenkopf… - JAIDS Journal of …, 2018 - journals.lww.com
Helicobacter pylori infects half of the world's population and strains that encode the cag type
IV secretion system for injection of the oncoprotein CagA into host gastric epithelial cells are …
IV secretion system for injection of the oncoprotein CagA into host gastric epithelial cells are …
MyD88 dimerization inhibitors for targeting Diffuse Large B-cell Lymphomas
…, S Taylor, M Sherman, R Beadenkopf… - The Journal of …, 2019 - journals.aai.org
A recurring single amino acid somatic mutation associated with human diffuse large B cell
lymphomas (DLBCLs), correlates with tumor cell proliferation and survival involving …
lymphomas (DLBCLs), correlates with tumor cell proliferation and survival involving …