Conformational properties of α-synuclein in its free and lipid-associated states
α-Synuclein (αS) is a presynaptic terminal protein that is believed to play an important role
in the pathogenesis of Parkinson’s disease (PD). We have used NMR spectroscopy to …
in the pathogenesis of Parkinson’s disease (PD). We have used NMR spectroscopy to …
A structural and functional role for 11-mer repeats in α-synuclein and other exchangeable lipid binding proteins
R Bussell Jr, D Eliezer - Journal of molecular biology, 2003 - Elsevier
We have used NMR spectroscopy and limited proteolysis to characterize the structural
properties of the Parkinson's disease-related protein α-synuclein in lipid and detergent micelle …
properties of the Parkinson's disease-related protein α-synuclein in lipid and detergent micelle …
Global chemical effects of the microbiome include new bile-acid conjugations
A mosaic of cross-phylum chemical interactions occurs between all metazoans and their
microbiomes. A number of molecular families that are known to be produced by the microbiome …
microbiomes. A number of molecular families that are known to be produced by the microbiome …
[HTML][HTML] Residual structure and dynamics in Parkinson's disease-associated mutants of α-synuclein
R Bussell, D Eliezer - Journal of Biological Chemistry, 2001 - ASBMB
α-Synuclein (αS) is a pre-synaptic protein that has been implicated as a possible causative
agent in the pathogenesis of Parkinson's disease (PD). Two autosomal dominant missense …
agent in the pathogenesis of Parkinson's disease (PD). Two autosomal dominant missense …
Control of the activity of CAR-T cells within tumours via focused ultrasound
Focused ultrasound can deliver energy safely and non-invasively into tissues at depths of
centimetres. Here we show that the genetics and cellular functions of chimeric antigen …
centimetres. Here we show that the genetics and cellular functions of chimeric antigen …
Helix periodicity, topology, and dynamics of membrane‐associated α‐Synuclein
R Bussell Jr, TF Ramlall, D Eliezer - Protein Science, 2005 - Wiley Online Library
The protein α‐Synuclein (aS) is a synaptic vesicle‐associated regulator of synaptic strength
and dopamine homeostasis with a pathological role in Parkinson's disease. The normal …
and dopamine homeostasis with a pathological role in Parkinson's disease. The normal …
Effects of Parkinson's disease-linked mutations on the structure of lipid-associated α-synuclein
R Bussell, D Eliezer - Biochemistry, 2004 - ACS Publications
α-Synuclein (αS) is a lipid-binding synaptic protein of unknown function that is found in an
aggregated amyloid fibril form in the intraneuronal Lewy body deposits that are a defining …
aggregated amyloid fibril form in the intraneuronal Lewy body deposits that are a defining …
Adolescents who kill
…, JR Hughes, J Arbit, RE Bussell - Journal of Clinical …, 1990 - Wiley Online Library
From a sample of 1,956 adolescent delinquents referred to us by the court for physical,
psychological, psychiatric, educational, and social examinations, 71 delinquents convicted of …
psychological, psychiatric, educational, and social examinations, 71 delinquents convicted of …
[HTML][HTML] Spatial encoding in primate hippocampus during free navigation
…, SU Nummela, M Metke, GW Diehl, R Bussell… - PLoS …, 2019 - journals.plos.org
The hippocampus comprises two neural signals—place cells and θ oscillations—that contribute
to facets of spatial navigation. Although their complementary relationship has been well …
to facets of spatial navigation. Although their complementary relationship has been well …
Awake mouse imaging: from two-photon microscopy to blood oxygen level–dependent functional magnetic resonance imaging
Background Functional magnetic resonance imaging (fMRI) in awake behaving mice is well
positioned to bridge the detailed cellular-level view of brain activity, which has become …
positioned to bridge the detailed cellular-level view of brain activity, which has become …