User profiles for Robert Jirsaraie

Robert Jirsaraie

Washington University in St. Louis
Verified email at wustl.edu
Cited by 232

[PDF][PDF] A systematic review of multimodal brain age studies: Uncovering a divergence between model accuracy and utility

RJ Jirsaraie, AJ Gorelik, MM Gatavins, DA Engemann… - Patterns, 2023 - cell.com
Brain aging is a complex, multifaceted process that can be challenging to model in ways that
are accurate and clinically useful. One of the most common approaches has been to apply …

[HTML][HTML] Leveraging multi-shell diffusion for studies of brain development in youth and young adulthood

…, A Adebimpe, DG Dávila, MA Elliott, R Jirsaraie… - Developmental cognitive …, 2020 - Elsevier
Diffusion weighted imaging (DWI) has advanced our understanding of brain microstructure
evolution over development. Recently, the use of multi-shell diffusion imaging sequences has …

Neural correlates of global and specific cognitive deficits in schizophrenia

RJ Jirsaraie, JM Sheffield, DM Barch - Schizophrenia research, 2018 - Elsevier
Cognitive deficits are a core feature of schizophrenia, but the neural mechanisms that contribute
to these characteristics are not fully understood. This study investigated whether volume …

Benchmarking the generalizability of brain age models: Challenges posed by scanner variance and prediction bias

RJ Jirsaraie, T Kaufmann, V Bashyam… - Human Brain …, 2023 - Wiley Online Library
Abstract Machine learning has been increasingly applied to neuroimaging data to predict
age, deriving a personalized biomarker with potential clinical applications. The scientific and …

Prenatal exposure to maternal mood entropy is associated with a weakened and inflexible salience network in adolescence

RJ Jirsaraie, AM Palma, SL Small, CA Sandman… - Biological Psychiatry …, 2024 - Elsevier
Background Fetal exposure to maternal mood dysregulation influences child cognitive and
emotional development, which may have long-lasting implications for mental health. However…

Early life stress moderates the relationship between age and prosocial behaviors

RJ Jirsaraie, KW Ranby, DS Albeck - Child Abuse & Neglect, 2019 - Elsevier
Background Several studies suggest that prosocial behaviors gradually increase with age,
but others report that prosocial behaviors are fixed traits with only minor fluctuations …

Accelerated cortical thinning within structural brain networks is associated with irritability in youth

RJ Jirsaraie, AN Kaczkurkin, S Rush, K Piiwia… - …, 2019 - nature.com
Irritability is an important dimension of psychopathology that spans multiple clinical diagnostic
categories, yet its relationship to patterns of brain development remains sparsely explored…

Timing and type of early psychopathology symptoms predict longitudinal change in cortical thickness from middle childhood into early adolescence

KR Luking, RJ Jirsaraie, R Tillman, JL Luby… - Biological psychiatry …, 2022 - Elsevier
Background Early-life experiences have profound effects on functioning in adulthood.
Altered cortical development may be one mechanism through which early-life experiences, …

Advantages of Multi-shell Diffusion Models for Studies of Brain Development in Youth

…, A Adebimpe, DG Dávila, MA Elliott, R Jirsaraie… - BioRxiv, 2019 - biorxiv.org
Diffusion-weighted imaging (DWI) has advanced our understanding of how brain microstructure
evolves during neurodevelopment. Most existing studies of brain development use a …