User profiles for Robert L. Last

Robert Last

University Distinguished Professor and Barnett Rosenberg Chair of Biochemistry and …
Verified email at msu.edu
Cited by 17355

Arabidopsis map-based cloning in the post-genome era

…, SD Rounsley, DF Bush, IM Levin, RL Last - Plant …, 2002 - academic.oup.com
Map-based cloning is an iterative approach that identifies the underlying genetic cause of a
mutant phenotype. The major strength of this approach is the ability to tap into a nearly …

Tryptophan biosynthesis and metabolism: biochemical and molecular genetics.

ER Radwanski, RL Last - The Plant Cell, 1995 - ncbi.nlm.nih.gov
Tryptophan is the one of the least abundant yet, in terms of energy, one of the most expensive
to produce of the standard protein amino acids (Hrazdina and Jensen, 1992). The Iow …

Arabidopsis flavonoid mutants are hypersensitive to UV-B irradiation.

…, TM Ou-Lee, R Raba, RG Amundson, RL Last - The Plant Cell, 1993 - academic.oup.com
Increases in the terrestrial levels of ultraviolet-B (UV-B) radiation (280 to 320 nm) due to
diminished stratospheric ozone have prompted an investigation of the protective mechanisms …

Arabidopsis mutants lacking phenolic sunscreens exhibit enhanced ultraviolet-B injury and oxidative damage

LG Landry, CCS Chapple, RL Last - Plant physiology, 1995 - academic.oup.com
We have assessed ultraviolet-B (UV-B)-induced injury in wild-type Arabidopsis thaliana and
two mutants with altered aromatic secondary product biosynthesis. Arabidopsis mutants …

Superoxide dismutase in Arabidopsis: an eclectic enzyme family with disparate regulation and protein localization

DJ Kliebenstein, RA Monde, RL Last - Plant physiology, 1998 - academic.oup.com
A number of environmental stresses can lead to enhanced production of superoxide within
plant tissues, and plants are believed to rely on the enzyme superoxide dismutase (SOD) to …

Environmental stress sensitivity of an ascorbic acid-deficient Arabidopsis mutant.

…, EH Williams, RL Last - Proceedings of the …, 1996 - National Acad Sciences
L-ascorbic acid (vitamin C) is a powerful reducing agent found in millimolar concentrations
in plants, and is proposed to play an important role in scavenging free radicals in plants and …

Genetic evidence for the role of GDP-mannose in plant ascorbic acid (vitamin C) biosynthesis

…, EH Williams, N Smirnoff, RL Last - Proceedings of the …, 1999 - National Acad Sciences
Vitamin C (l-ascorbic acid; AsA) acts as a potent antioxidant and cellular reductant in plants
and animals. AsA has long been known to have many critical physiological roles in plants, …

Harnessing plant trichome biochemistry for the production of useful compounds

AL Schilmiller, RL Last, E Pichersky - The Plant Journal, 2008 - Wiley Online Library
Plant trichomes come in a variety of shapes, sizes and cellular composition. Some types,
commonly called glandular trichomes, produce large amounts of specialized (secondary) …

Arabidopsis UVR8 Regulates Ultraviolet-B Signal Transduction and Tolerance and Contains Sequence Similarity to Human Regulator of Chromatin Condensation 1

DJ Kliebenstein, JE Lim, LG Landry, RL Last - Plant physiology, 2002 - academic.oup.com
To further our understanding of how plants defend against the harmful effects of ultraviolet (UV)
light, we characterized an Arabidopsis mutant hypersensitive to UV-B. This mutant, UV …

Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate

…, A Schmidt, C Wilkerson, RL Last… - Proceedings of the …, 2009 - National Acad Sciences
We identified a cis-prenyltransferase gene, neryl diphosphate synthase 1 (NDPS1), that is
expressed in cultivated tomato (Solanum lycopersicum) cultivar M82 type VI glandular …