User profiles for Robert Leech

Robert Leech

King's College London
Verified email at kcl.ac.uk
Cited by 22555

The role of the posterior cingulate cortex in cognition and disease

R Leech, DJ Sharp - Brain, 2014 - academic.oup.com
The posterior cingulate cortex is a highly connected and metabolically active brain region.
Recent studies suggest it has an important cognitive role, although there is no consensus …

Fractionating the default mode network: distinct contributions of the ventral and dorsal posterior cingulate cortex to cognitive control

R Leech, S Kamourieh, CF Beckmann… - Journal of …, 2011 - Soc Neuroscience
The posterior cingulate cortex (PCC) is a central part of the default mode network (DMN)
and part of the structural core of the brain. Although the PCC often shows consistent …

The default mode network in cognition: a topographical perspective

J Smallwood, BC Bernhardt, R Leech… - Nature reviews …, 2021 - nature.com
The default mode network (DMN) is a set of widely distributed brain regions in the parietal,
temporal and frontal cortex. These regions often show reductions in activity during attention-…

Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin

…, A Colasanti, RJ Tyacke, R Leech… - Proceedings of the …, 2012 - National Acad Sciences
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed
interest in their therapeutic potential, we continue to know very little about how they work in the …

Network dysfunction after traumatic brain injury

DJ Sharp, G Scott, R Leech - Nature Reviews Neurology, 2014 - nature.com
Diffuse axonal injury after traumatic brain injury (TBI) produces neurological impairment by
disconnecting brain networks. This structural damage can be mapped using diffusion MRI, …

[HTML][HTML] The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs

RL Carhart-Harris, R Leech, PJ Hellyer… - Frontiers in human …, 2014 - frontiersin.org
Entropy is a dimensionless quantity that is used for measuring uncertainty about the state of
a system but it can also imply physical qualities, where high entropy is synonymous with …

Neural correlates of the LSD experience revealed by multimodal neuroimaging

…, T Nest, C Orban, R Leech… - Proceedings of the …, 2016 - National Acad Sciences
Lysergic acid diethylamide (LSD) is the prototypical psychedelic drug, but its effects on the
human brain have never been studied before with modern neuroimaging. Here, three …

White matter damage and cognitive impairment after traumatic brain injury

KM Kinnunen, R Greenwood, JH Powell, R Leech… - Brain, 2011 - academic.oup.com
White matter disruption is an important determinant of cognitive impairment after brain injury,
but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor …

Echoes of the brain within the posterior cingulate cortex

R Leech, R Braga, DJ Sharp - Journal of Neuroscience, 2012 - Soc Neuroscience
There is considerable uncertainty about the function of the posterior cingulate cortex (PCC).
The PCC is a major node within the default mode network (DMN) and has high metabolic …

Salience network integrity predicts default mode network function after traumatic brain injury

V Bonnelle, TE Ham, R Leech… - Proceedings of the …, 2012 - National Acad Sciences
Efficient behavior involves the coordinated activity of large-scale brain networks, but the
way in which these networks interact is uncertain. One theory is that the salience network (SN)—…