Raman spectroscopy for cancer detection and cancer surgery guidance: translation to the clinics

…, RWH Smits, R Van Doorn, RM Verdijk… - Analyst, 2017 - pubs.rsc.org
Oncological applications of Raman spectroscopy have been contemplated, pursued, and
developed at academic level for at least 25 years. Published studies aim to detect pre-…

[HTML][HTML] Conjunctival melanoma: New insights in tumour genetics and immunology, leading to new therapeutic options

…, RM Verdijk, S Heegaard, M Marinkovic… - Progress in Retinal and …, 2022 - Elsevier
Recent developments in oncology have led to a better molecular and cellular understanding
of cancer, and the introduction of novel therapies. Conjunctival melanoma (CoM) is a rare …

Placental tissue destruction and insufficiency from COVID-19 causes stillbirth and neonatal death from hypoxic-ischemic injury: a study of 68 cases with SARS-CoV-2 …

…, RM Verdijk, JC Watkins, M Zaigham - … of pathology & …, 2022 - meridian.allenpress.com
Context.— Perinatal death is an increasingly important problem as the coronavirus disease
2019 (COVID-19) pandemic continues, but the mechanism of death has been unclear. …

Uveal melanomas with SF3B1 mutations: a distinct subclass associated with late-onset metastases

S Yavuzyigitoglu, AE Koopmans, RM Verdijk… - Ophthalmology, 2016 - Elsevier
Purpose To investigate the prevalence and prognostic value of SF3B1 and EIF1AX mutations
in uveal melanoma (UM) patients. Design Case series. Participants Cohort of 151 patients …

[HTML][HTML] Clinical significance of immunohistochemistry for detection of BAP1 mutations in uveal melanoma

AE Koopmans, RM Verdijk, RWW Brouwer… - Modern …, 2014 - nature.com
Uveal melanoma is a lethal cancer with a strong propensity to metastasize. Limited
therapeutic options are available once the disease has disseminated. A strong predictor for …

The treatment outcomes in IgG4‐related orbital disease: a systematic review of the literature

SE Detiger, AF Karim, RM Verdijk… - Acta …, 2019 - Wiley Online Library
IgG4‐related disease (IgG4‐ RD ) is an immune‐mediated systemic fibro inflammatory disease.
Treatment of IgG4‐related orbital disease (IgG4‐ ROD ) is often indicated to relieve the …

ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition

…, JAM van Laar, RM Verdijk… - Blood, The Journal …, 2022 - ashpublications.org
ALK-positive histiocytosis is a rare subtype of histiocytic neoplasm first described in 2008 in
3 infants with multisystemic disease involving the liver and hematopoietic system. This entity …

Anti‐LGI1 encephalitis is strongly associated with HLA‐DR7 and HLA‐DRB4

…, DL Roelen, JA Stoop, RM Verdijk… - Annals of …, 2017 - Wiley Online Library
Leucine‐rich glioma‐inactivated1 (LGI1) encephalitis is an antibody‐associated inflammation
of the limbic area. An autoimmune etiology is suspected but not yet proven. We performed …

Polyriboinosinic polyribocytidylic acid (poly (I: C)) induces stable maturation of functionally active human dendritic cells

RM Verdijk, T Mutis, B Esendam, J Kamp… - The Journal of …, 1999 - journals.aai.org
For vaccination strategies and adoptive immunotherapy purposes, immature dendritic cells (DC)
can be generated from adherent monocytes using GM-CSF and IL-4. Presently, the only …

[HTML][HTML] Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment

…, PA van der Velden, V Walter, RM Verdijk… - Cancer Immunology …, 2017 - Springer
Uveal melanoma (UM) is characterized by a number of genetic aberrations that follow a certain
chronology and are tightly linked to tumor recurrence and survival. Loss of chromosome 3…