User profiles for Robert Milan Porsch

Robert Porsch

The University of Hong Kong
Verified email at hku.hk
Cited by 647

Polygenic scores via penalized regression on summary statistics

TSH Mak, RM Porsch, SW Choi, X Zhou… - Genetic …, 2017 - Wiley Online Library
Polygenic scores (PGS) summarize the genetic contribution of a person's genotype to a
disease or phenotype. They can be used to group participants into different risk categories for …

[PDF][PDF] Polygenic scores for UK Biobank scale data

TSH Mak, RM Porsch, SW Choi, PC Sham - BioRxiv, 2018 - pdfs.semanticscholar.org
Polygenic scores (PGS) are estimated scores representing the genetic tendency of an individual
for a 2 disease or trait and have become an indispensible tool in a variety of analyses. …

Polygenic scores without external summary statistics

TS Heng Mak, RM Porsch, SW Choi, PC Sham - bioRxiv, 2018 - biorxiv.org
Polygenic scores (PGS) are estimated scores representing the genetic tendency of an
individual for a disease or trait and have become an indispensible tool in a variety of analyses. …

Application and development of quantitative methods to explore the genetic architecture of human aggression

RM Porsch - HKU Theses Online (HKUTO), 2017 - hub.hku.hk
Aggression is the delivery of an aversive stimulus from one person to another with intent to
cause harm. Such behavior has potential beneficial and harmful consequences for the …

1–14 Prélude: Macrophages in Inflammation/15–35 Macrophages in Anti-Inflammation: Molecular Mechanisms/36–46 Macrophages in Anti-Inflammation: Apoptosis …

…, I Eue, G Schmitz, WE Kaminski, M Porsch-Özcürümez… - Pathobiology, 1999 - karger.com
Scavenger receptors (SRs) are membrane glycoproteins that are defined by their capacity
to bind modified lipoproteins and thereby influence atherogenesis. However, accumulating …

PRS-Net: Interpretable polygenic risk scores via geometric learning

H Li, J Zeng, M Snyder, S Zhang - bioRxiv, 2024 - biorxiv.org
Polygenic risk score (PRS) serves as a valuable tool for predicting the genetic risk of complex
human diseases for individuals, playing a pivotal role in advancing precision medicine. …

[PDF][PDF] Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores

F Privé, J Arbel, H Aschard, BJ Vilhjálmsson - Human Genetics and …, 2022 - cell.com
… LDpred2-low-h2 and LDpred2-auto-rob Here we introduce the small changes made to
LDpred2 (-grid and -auto) in order to make them more robust. First, LDpred2-low-h2 simply …

[BOOK][B] Some Statistical Methods for Polygenic Modeling and Genetic Prediction in Large Biobanks

J Song - 2022 - search.proquest.com
Polygenic risk scores (PRS) are predictors for individuals’ genetic susceptibilities to disease.
The standard protocol for generating PRS requires an external genome-wide association …

[BOOK][B] The Catholic Encyclopedia: An International Work of Reference on the Constitution, Doctrine, Discipline, and History of the Catholic Church

AA MacErlean - 1914 - books.google.com
As originally planned and announced The Catholic Encyclopedia was not to have an Index
Volume. The editors were of the opinion that the alphabetical order of the articles and …

[BOOK][B] Founders of American industrial design

C Gantz - 2014 - books.google.com
As the Great Depression started in 1929, several dozen creative individuals from a variety of
artistic fields, including theatre, advertising, graphics, fashion and furniture design, …