Gut bacteria modulate the response to immune checkpoint blockade (ICB) treatment in cancer,
but the effect of diet and supplements on this interaction is not well studied. We assessed …

The gastrointestinal tracts of mammals are colonized by hundreds of microbial species that
contribute to health, including colonization resistance against intestinal pathogens 1 . Many …

Epithelial regeneration is critical for barrier maintenance and organ function after intestinal
injury. The intestinal stem cell (ISC) niche provides Wnt, Notch and epidermal growth factor (…

Background . Bacteremia is a frequent complication of allogeneic hematopoietic stem cell
transplantation (allo-HSCT). It is unclear whether changes in the intestinal microbiota during …

Bloodstream infection by highly antibiotic-resistant bacteria, such as vancomycin-resistant
Enterococcus (VRE), is a growing clinical problem that increasingly defies medical intervention…

Ipilimumab improves clinical outcomes when combined with nivolumab in metastatic non-small
cell lung cancer (NSCLC), but its efficacy and impact on the immune microenvironment …

Highly diverse bacterial populations inhabit the gastrointestinal tract and modulate host
inflammation and promote immune tolerance. In allogeneic hematopoietic stem cell …

Abstract Treatment with combined immune checkpoint blockade (CICB) targeting CTLA-4 and
PD-1 is associated with clinical benefit across tumor types, but also a high rate of immune-…

The relationship between intestinal microbiota composition and acute graft-versus-host disease
(GVHD) after allogeneic blood/marrow transplantation (allo-BMT) is not well understood. …

Despite a growing understanding of the link between intestinal inflammation and resident gut
microbes, longitudinal studies of human flora before initial onset of intestinal inflammation …