Considerable debate remains regarding the distinct biological activities of individual
polyunsaturated fatty acids (PUFA). One of the most interesting yet controversial dietary approaches …

The inflammatory response is designed to help fight and clear infection, remove harmful
chemicals, and repair damaged tissue and organ systems. Although this process, in general, is …

The tryptophan metabolites indole, indole-3-acetate, and tryptamine were identified in mouse
cecal extracts and fecal pellets by mass spectrometry. The aryl hydrocarbon receptor (AHR…

Background Gut microbiota and the host exist in a mutualistic relationship, with the functional
composition of the microbiota strongly affecting the health and well-being of the host. Thus, …

Objectives: This study tested the hypothesis that the fecal bacterial genera of breast-fed (BF)
and formula-fed (FF) infants differ and that human milk oligosaccharides (HMOs) modulate …

In vitro evidence indicates that (n-3) polyunsaturated fatty acids (PUFA) suppress T-cell
activation in part by displacing proteins from lipid rafts, specialized regions within the plasma …

To date, the proximal molecular targets through which dietary n-3 polyunsaturated fatty acids
(PUFA) suppress the inflammatory process have not been elucidated. Because cholesterol …

Elucidation of the mechanism(s) by which dietary fish oil, enriched in eicosapentaenoic acid
[EPA, 20:5(n-3)] and docosahexaenoic acid [DHA, 22:6(n-3)], suppresses the inflammatory …

Fish oil, enriched in bioactive n-3 polyunsaturated fatty acids (PUFA), has been shown to
play a role in prevention of colon cancer. The effects of n-3 PUFA are pleiotropic and …

In recent years, our understanding of the plasma membrane has changed considerably as
our knowledge of lipid microdomains has expanded. Lipid microdomains include structures …