THE cellular prion protein (PrP c ) is a sialoglycoprotein of M r 33–35K that is expressed
predominantly in neurons 1–3 . In transmissible and genetic neurodegenerative disorders such …

1.1. Purpose The European Society for Vascular Surgery (ESVS) appointed the Descending
Thoracic Aorta (DTA) Writing Committee (WC) to produce the current clinical practice …

1.1 Purpose The last decade has substantially broadened treatment options for patients
with thoracic aortic pathology involving the aortic arch. Traditionally, treatment of aortic arch …

Inability to form new memories is an early clinical sign of Alzheimer’s disease (AD). There is
ample evidence that the amyloid-β (Aβ) peptide plays a key role in the pathogenesis of this …

Objectives : This study was designed to evaluate contrast-enhanced ultrasound imaging of
carotid atherosclerosis as a clinical tool to study intraplaque neovascularization. Background …

Wear was analyzed on 21 metal on metal hip replacements, including McKee-Farrar, Müller,
and Ring, that were retrieved from patients after as many as 25 years. Light and scanning …

High mobility group box 1 protein (HMGB1) is a chromatin component leaked out by necrotic
cells and actively secreted by activated myeloid cells. The extracellular protein is a potent …

Familial prion diseases are caused by mutations in the gene encoding the prion protein (PrP).
We have produced transgenic mice that express the mouse homolog of a mutant human …

OBJECTIVES: Neurologic deficit after endovascular treatment of the thoracic aorta is a
complication reported with variable frequency that may be associated with severe morbidity and …

The influence of different surface preparations on titanium biocompatibility and bone
integration was evaluated. Commercially grade 2 titanium rods (∅2mm, length: 3mm), vacuum …