We report here that rings of rat aorta embedded in gels of fibrin or collagen and cultured in
MCDB 131, an optimized growth medium for microvascular endothelial cells, generate …

The α v β 3 integrin plays a fundamental role during the angiogenesis process by inhibiting
endothelial cell apoptosis. However, the mechanism of inhibition is unknown. In this report, …

The formation of new blood vessels, or angiogenesis, is a complex process that plays important
roles in growth and development, tissue and organ regeneration, as well as numerous …

Rings of rat aorta cultured in Matrigel, a reconstituted gel composed of basement membrane
molecules, gave rise to three-dimensional networks composed of solid cellular cords and …

Rationale & Objective Kidney biopsy data inform us about pathologic processes associated
with infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We …

Patients with coronavirus disease 2019 (COVID-19) who are critically ill develop vascular
complications characterized by thrombosis of small, medium, and large vessels. Dysfunction of …

Fibronectin is a component of the extracellular matrix of developing microvessels whose role
in angiogensis is poorly understood. This study evaluated the effect of plasma fibronectin …

Angiogenesis is regulated by a complex cascade of cellular and molecular events. The
entire process can be reproduced in vitro by culturing rat or mouse aortic explants in three‐…

Thrombospondin (TSP) is a multidomain adhesive protein postulated to play an important
role in the biological activity of the extracellular matrix. To test this hypothesis, TSP-containing …

Vascular dysfunction is a hallmark of chronic diseases in elderly. The contribution of the
vasculature to lung repair and fibrosis is not fully understood. Here, we performed an epigenetic …