The CEBPA gene is mutated in 9% of patients with acute myeloid leukemia (AML). Selective
expression of a short (30-kDa) CCAAT-enhancer binding protein-α (C/EBPα) translational …

The analysis of individuals with severe congenital neutropenia (SCN) may shed light on the
delicate balance of factors controlling the differentiation, maintenance and decay of …

The retrospective nature of our study, as well as the relatively small number ofFLT3-ITD 1
AML patients included in the analysis, is the most serious limitation of the obtained data. Our …

Protein arginine methyltransferase 1 (PRMT1) is overexpressed in various human cancers
and linked to poor response to chemotherapy. Various PRMT1 inhibitors are currently under …

Facioscapulohumeral muscular dystrophy (FSHD) is one of the most prevalent neuromuscular
disorders. The disease is linked to copy number reduction and/or epigenetic alterations of …

The SARS-CoV-2 virus has a complex transcriptome characterised by multiple, nested
subgenomic RNAsused to express structural and accessory proteins. Long-read sequencing …

Phosphoanhydrides (P‐anhydrides) are ubiquitously occurring modifications in nature.
Nucleotides and their conjugates, for example, are among the most important building blocks …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive single-stranded
RNA virus, engages in complex interactions with host cell proteins throughout its life cycle. …

MicroRNA (miRNA) biogenesis is a tightly controlled multi-step process operated in the nucleus
by the activity of the Microprocessor and its associated proteins. Through high resolution …

Mixed-lineage leukemia 1 (MLL1) is a transcription activator of the HOX family, which binds
to specific epigenetic marks on histone H3 through its third plant homeodomain (PHD3) …