Curcumin, the primary curcuminoid compound found in turmeric spice, has shown broad
activity as an antimicrobial agent, limiting the replication of many different fungi, bacteria and …

For more than half a century, researchers have studied the basic biology of Adenovirus (Ad),
unraveling the subtle, yet profound, interactions between the virus and the host. These …

Several targeted therapies have shown efficacy in patients with advanced gastric cancer (GC)
and gastroesophageal junction adenocarcinoma (GEJC), including anti-angiogenic …

Mutations in the LRRK2 gene are the most common genetic cause of familial Parkinson's
disease (PD). However, its physiological and pathological functions are unknown. Therefore, …

The innate immune system recognizes nucleic acids during infection and tissue damage.
Whereas viral RNA is detected by endosomal toll-like receptors (TLR3, TLR7, TLR8) and …

Adenoviruses are attractive vectors for the delivery of foreign genes into mammalian cells
for gene therapy. However, current vectors retain many viral genes that, when expressed at …

Many applications for human gene therapy would be facilitated by high levels and long duration
of physiologic gene expression. Adenoviral vectors are frequently used for gene transfer …

Extensive analyses of mice carrying null mutations in paired box 7 (Pax7) have confirmed
the progressive loss of the satellite cell lineage in skeletal muscle, resulting in severe muscle …

NADPH oxidase (Nox) enzymes are a significant source of reactive oxygen species, which
contribute to glomerular podocyte dysfunction. Although studies have implicated Nox1,-2, and…

Differential Scanning Calorimetry (DSC) has been used to study the thermal properties of fish
muscle proteins and to measure the extent of their denaturation under various processing …