Enhancer elements in the human genome control how genes are expressed in specific cell
types and harbor thousands of genetic variants that influence risk for common diseases 1 , 2 , …

Gene expression in mammals is regulated by noncoding elements that can affect physiology
and disease, yet the functions and target genes of most noncoding elements remain …

Behavior is shaped by both the internal state of an animal and its individual behavioral biases.
Rhythmic variation in gonadal hormones during the estrous cycle is a defining feature of …

Understanding how genes, drugs and neural circuits influence behavior requires the ability
to effectively organize information about similarities and differences within complex …

Animals both explore and avoid novel objects in the environment, but the neural mechanisms
that underlie these behaviors and their dynamics remain uncharacterized. Here, we used …

Mammalian genomes harbor millions of noncoding elements called enhancers that
quantitatively regulate gene expression, but it remains unclear which enhancers regulate which …

High expression of MYC and its target genes define a subset of germinal center B-cell diffuse
large B-cell lymphoma (GCB-DLBCL) associated with poor outcomes. Half of these high-…