Extracellular vesicles (EVs) are small bilayer lipid membrane vesicles that can be released
by most cell types and detected in most body fluids. EVs exert key functions for intercellular …

Population isolates such as those in Finland benefit genetic research because deleterious
alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor …

Population isolates such as Finland provide benefits in genetic studies because the allelic
spectrum of damaging alleles in any gene is often concentrated on a small number of low-…

Extracellular RNA (exRNA) has recently expanded as a highly important area of study in
biomarker discovery and cancer therapeutics. exRNA consists of diverse RNA subpopulations …

Extracellular RNA (exRNA) has emerged as an important transducer of intercellular communication.
Advancing exRNA research promises to revolutionize biology and transform clinical …

Poor reproducibility within and across studies arising from lack of knowledge regarding the
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …

Rationale: Previous translational studies implicate plasma extracellular microRNA-30d (miR-30d)
as a biomarker in left ventricular remodeling and clinical outcome in heart failure (HF) …

Context Underlying mechanisms leading to gestational diabetes mellitus (GDM) are still
under investigation, and it is unclear whether the placenta plays a role in triggering glucose …

Background Air pollution from particulate matter (PM) has been linked to cardiovascular
morbidity and mortality; however the underlying biological mechanisms remain to be uncovered. …

Background: The heart grows in response to pathological and physiological stimuli. The former
often precedes cardiomyocyte loss and heart failure; the latter paradoxically protects the …