Tremendous progress has been made over the last ten years on East Coast fever (ECF)
research. Publication of a reference genome sequence of Theileria parva, the causative agent …

East Coast fever, caused by the tick-borne intracellular apicomplexan parasite Theileria
parva, is a highly fatal lymphoproliferative disease of cattle. The pathogenic schizont-induced …

African swine fever (ASF) caused by the African swine fever virus (ASFV) is ranked by OIE as
the most important source of mortality in domestic pigs globally and is indigenous to African …

Background Ticks and tick-borne diseases are a major impediment to livestock production
worldwide. Cattle trade and transnational transhumance create risks for the spread of ticks …

African swine fever (ASF) is the most important disease constraining smallholder pig
production in the Democratic Republic of Congo, causing high mortality in domestic pigs with …

Background Theileria parva causes an acute fatal disease in cattle, but infections are
asymptomatic in the African buffalo (Syncerus caffer). Cattle can be immunized against the parasite …

African swine fever (ASF) is a highly infectious and fatal haemorrhagic disease of pigs that is
caused by a complex DNA virus of the genus Asfivirus and Asfarviridae African suids family. …

Immunity against the bovine intracellular protozoan parasite Theileria parva has been
shown to be mediated by CD8 T cells. Six antigens targeted by CD8 T cells from T. parva-immune …

The purine salvage pathway of parasitic protozoa is currently considered as a target for drug
development because these organisms cannot synthesize purines de novo. Insight into the …

Although immunodominance of CD8 + T‐cell responses is a well‐recognised feature of viral
infections, its role in responses to more antigenically complex pathogens is less clear. In …