Inhibitory activity of cyclohexenyl chalcone derivatives and flavonoids of fingerroot, Boesenbergia rotunda (L.), towards dengue-2 virus NS3 protease
Boesenbergia rotunda (L.) cyclohexenyl chalcone derivatives, 4-hydroxypanduratin A and
panduratin A, showed good competitive inhibitory activities towards dengue 2 virus NS3 …
panduratin A, showed good competitive inhibitory activities towards dengue 2 virus NS3 …
[HTML][HTML] Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro
R Yusof, S Clum, M Wetzel, HMK Murthy… - Journal of Biological …, 2000 - ASBMB
Dengue virus type 2 NS3, a multifunctional protein, has a serine protease domain (NS3pro)
that requires the conserved hydrophilic domain of NS2B for protease activity in cleavage of …
that requires the conserved hydrophilic domain of NS2B for protease activity in cleavage of …
Inhibitory effect of doxycycline against dengue virus replication in vitro
Doxycycline is an antibiotic derived from tetracycline that possesses antimicrobial and anti-inflammatory
activities. Antiviral activity of doxycycline against dengue virus has been …
activities. Antiviral activity of doxycycline against dengue virus has been …
Carnosine exhibits significant antiviral activity against Dengue and Zika virus
…, N Nor Rashid, TT Chong, R Yusof - Journal of Peptide …, 2019 - Wiley Online Library
Dengue virus (DENV) and Zika virus (ZIKV) are flaviviruses transmitted to humans by their
common vector, Aedes mosquitoes. DENV infection represents one of the most widely spread …
common vector, Aedes mosquitoes. DENV infection represents one of the most widely spread …
[HTML][HTML] Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae
family. B. rotunda is widely found in Asian countries where it is commonly used as a food …
family. B. rotunda is widely found in Asian countries where it is commonly used as a food …
[HTML][HTML] Endoplasmic reticulum: a focal point of Zika virus infection
…, AS Khazali, N Nor Rashid, R Yusof - Journal of biomedical …, 2020 - Springer
Zika virus (ZIKV) belongs to the Flavivirus genus of the Flaviviridae family. It is an arbovirus
that can cause congenital abnormalities and is sexually transmissible. A series of outbreaks …
that can cause congenital abnormalities and is sexually transmissible. A series of outbreaks …
The importance of some plant extracts as skin anti-aging resources: a review
Background: Skin is the largest and most visible organ of the body. Many of its functions include
temperature regulation, immunity from microorganisms, maintaining electrolyte balance, …
temperature regulation, immunity from microorganisms, maintaining electrolyte balance, …
[HTML][HTML] A combination of doxycycline and ribavirin alleviated chikungunya infection
…, TC Teoh, EM Shankar, NA Rahman, R Yusof - PloS one, 2015 - journals.plos.org
Lack of vaccine and effective antiviral drugs against chikungunya virus (CHIKV) outbreaks
have led to significant impact on health care in the developing world. Here, we evaluated the …
have led to significant impact on health care in the developing world. Here, we evaluated the …
[HTML][HTML] Inhibition of dengue NS2B-NS3 protease and viral replication in Vero cells by recombinant retrocyclin-1
Background Global resurgence of dengue virus infections in many of the tropical and subtropical
countries is a major concern. Therefore, there is an urgent need for the development of …
countries is a major concern. Therefore, there is an urgent need for the development of …
[HTML][HTML] Protegrin-1 inhibits dengue NS2B-NS3 serine protease and viral replication in MK2 cells
…, S Othman, N Abd Rahman, R Yusof - BioMed Research …, 2012 - hindawi.com
Dengue diseases have an economic as well as social burden worldwide. In this study, the
antiviral activity of protegrin-1 (PG-1, RGGRLCYCRRRFCVCVGR) peptide towards dengue …
antiviral activity of protegrin-1 (PG-1, RGGRLCYCRRRFCVCVGR) peptide towards dengue …