User profiles for Roland Contreras

Roland Contreras

Ghent University
Verified email at ugent.be
Cited by 16098

[HTML][HTML] Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88

…, S Breestraat, MX Caddick, R Contreras… - Nature …, 2007 - nature.com
The filamentous fungus Aspergillus niger is widely exploited by the fermentation industry for
the production of enzymes and organic acids, particularly citric acid. We sequenced the 33.9-…

Complete nucleotide sequence of SV40 DNA

W Fiers, R Contreras, G Haegeman, R Rogiers… - Nature, 1978 - nature.com
The determination of the total 5,224 base-pair DNA sequence of the virus SV40 has enabled
us to locate precisely the known genes on the genome. At least 15.2% of the genome is …

Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene

W Fiers, R Contreras, F Duerinck, G Haegeman… - Nature, 1976 - nature.com
Bacteriophage MS2 RNA is 3,569 nucleotides long. The nucleotide sequence has been
established for the third and last gene, which codes for the replicase protein. A secondary …

Human antimicrobial peptides: defensins, cathelicidins and histatins

K De Smet, R Contreras - Biotechnology letters, 2005 - Springer
Antimicrobial peptides, which have been isolated from many bacteria, fungi, plants,
invertebrates and vertebrates, are an important component of the natural defenses of most living …

Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N …

…, N Callewaert, R Contreras… - Proceedings of the …, 2002 - National Acad Sciences
An HEK293S cell line resistant to ricin was prepared by mutagenesis by using ethyl
methanesulfonate. It was shown to lack N-acetylglucosaminyltransferase I (GnTI) activity, and …

Noninvasive diagnosis of liver cirrhosis using DNA sequencer–based total serum protein glycomics

…, AV Hecke, W Laroy, J Delanghe, R Contreras - Nature medicine, 2004 - nature.com
We applied our 'clinical glycomics' technology, based on DNA sequencer/fragment analyzers,
to generate profiles of serum protein N-glycans of liver disease patients. This technology …

The zinc finger protein A20 inhibits TNF-induced NF-κB–dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal and directly …

…, WV Berghe, W Van Criekinge, R Contreras… - The Journal of cell …, 1999 - rupress.org
The zinc finger protein A20 is a tumor necrosis factor (TNF)– and interleukin 1 (IL-1)-inducible
protein that negatively regulates nuclear factor-kappa B (NF-κB)–dependent gene …

Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology

PP Jacobs, S Geysens, W Vervecken, R Contreras… - Nature protocols, 2009 - nature.com
Roland Contreras … Pieter P Jacobs, Steven Geysens, Wouter Vervecken, Roland
Contreras & Nico Callewaert … Roland Contreras

In Vivo Synthesis of Mammalian-Like, Hybrid-Type N-Glycans in Pichia pastoris

…, S Geysens, K De Vusser, R Contreras - Applied and …, 2004 - Am Soc Microbiol
The Pichia pastoris N-glycosylation pathway is only partially homologous to the pathway in
human cells. In the Golgi apparatus, human cells synthesize complex oligosaccharides, …

Glycome mapping on DNA sequencing equipment

W Laroy, R Contreras, N Callewaert - Nature protocols, 2006 - nature.com
Here we provide a detailed protocol for the analysis of protein-linked glycans on DNA sequencing
equipment. This protocol satisfies the glyco-analytical needs of many projects and can …