Multivalency plays a major role in biological processes and particularly in the relationship
between pathogenic microorganisms and their host that involves protein–glycan recognition. …

Multivalent carbohydrates are currently produced in many forms ranging from dendrimers,
polymers, micelles, vesicles, nanoparticles to functionalized nanotubes, in order to enhance …

Carbohydrate–protein interactions are involved in a multitude of biological recognition
processes. Since individual protein–carbohydrate interactions are usually weak, multivalency is …

Discovery of glycan‐competitive galectin‐3‐binding compounds that attenuate lung fibrosis
in a murine model and that block intracellular galectin‐3 accumulation at damaged vesicles, …

Galectins are mammalian carbohydrate‐binding proteins that are involved in cell–cell and
cell–matrix adhesion, cell migration, and growth regulation with relevance to inflammation …

Bacterial adhesion is often a prelude to infection. In many cases, this process is governed
by protein–carbohydrate interactions. Intervention at this early stage of infection is a …

Carbohydrates participate in almost every aspect of biology from protein sorting to modulating
cell differentiation and cell–cell interactions. To date, the majority of data gathered on …

Interest in the synthesisand chemistry of the cyclopropane subunit may be attributed to a
number of factors including its occurrence in natural products, 1 its biological significance, 2 its …

The extracellular functions of galectin-7 (p53-induced gene 1) are largely unknown. On the
surface of neuroblastoma cells (SK-N-MC), the increased GM 1 density, a result of …

Chemical cross-linking mass spectrometry is rapidly emerging as a prominent technique to
study protein structures. Structural information is obtained by covalently connecting peptides …