User profiles for Roland Le Borgne
Roland Le BorgneCNRS Research Director Verified email at univ-rennes1.fr Cited by 5413 |
Drosophila S2 cells secrete wingless on exosome‐like vesicles but the wingless gradient forms independently of exosomes
…, H Green, E Bonneil, G Raposo, P Thibault, RL Borgne… - Traffic, 2013 - Wiley Online Library
Wingless acts as a morphogen in Drosophila wing discs, where it specifies cell fates and
controls growth several cell diameters away from its site of expression. Thus, despite being …
controls growth several cell diameters away from its site of expression. Thus, despite being …
Ezrin has properties to self-associate at the plasma membrane
Ezrin, a member of a family of proteins involved in the interaction of the microfilament cytoskeleton
with the plasma membrane, plays a role in membrane translocation in gastric parietal …
with the plasma membrane, plays a role in membrane translocation in gastric parietal …
Mannose 6-phosphate receptors regulate the formation of clathrin-coated vesicles in the TGN
RL Borgne, B Hoflack - The Journal of cell biology, 1997 - rupress.org
The transport of the two mannose 6-phosphate receptors (MPRs) from the secretory
pathway to the endocytic pathway is mediated by carrier vesicles coated with the AP-1 Golgi-specific …
pathway to the endocytic pathway is mediated by carrier vesicles coated with the AP-1 Golgi-specific …
Small and stable peptidic PEGylated quantum dots to target polyhistidine-tagged proteins with controlled stoichiometry
…, P Neveu, F Vignaux, RL Borgne… - Journal of the …, 2009 - ACS Publications
The use of the semiconductor quantum dots (QD) as biolabels for both ensemble and single-molecule
tracking requires the development of simple and versatile methods to target …
tracking requires the development of simple and versatile methods to target …
Genetic identification of intracellular trafficking regulators involved in Notch-dependent binary cell fate acquisition following asymmetric cell division
…, G Kriegel-Taki, A Dussert, RL Borgne - Journal of cell …, 2012 - journals.biologists.com
Notch signalling is involved in numerous cellular processes during development and throughout
adult life. Although ligands and receptors are largely expressed in the whole organism, …
adult life. Although ligands and receptors are largely expressed in the whole organism, …
Assembly, dynamics and remodeling of epithelial cell junctions throughout development
M Mira-Osuna, RL Borgne - Development, 2024 - journals.biologists.com
Cell junctions play key roles in epithelial integrity. During development, when epithelia
undergo extensive morphogenesis, these junctions must be remodeled in order to maintain …
undergo extensive morphogenesis, these junctions must be remodeled in order to maintain …
Cell-intrinsic and -extrinsic roles of the ESCRT-III subunit Shrub in abscission of Drosophila sensory organ precursors
Although the molecular mechanisms governing abscission of isolated cells have largely
been elucidated, those underlying the abscission of epithelial progenitors surrounded by …
been elucidated, those underlying the abscission of epithelial progenitors surrounded by …
The roles of receptor and ligand endocytosis in regulating Notch signaling
R Le Borgne, A Bardin, F Schweisguth - 2005 - journals.biologists.com
Cell-cell signaling is a central process in the formation of multicellular organisms. Notch (N)
is the receptor of a conserved signaling pathway that regulates numerous developmental …
is the receptor of a conserved signaling pathway that regulates numerous developmental …
Regulation of Notch signalling by endocytosis and endosomal sorting
R Le Borgne - Current opinion in cell biology, 2006 - Elsevier
Cell–cell signalling is an essential process in the formation of multicellular organisms. Notch
is the receptor of an evolutionarily conserved signalling pathway regulating numerous …
is the receptor of an evolutionarily conserved signalling pathway regulating numerous …
ESCRT-III-dependent adhesive and mechanical changes are triggered by a mechanism detecting alteration of Septate Junction integrity in Drosophila epithelial cells
…, MK Jaglarz, E Durel, R Le Borgne - Elife, 2024 - elifesciences.org
Barrier functions of proliferative epithelia are constantly challenged by mechanical and chemical
constraints. How epithelia respond to and cope with disturbances of barrier functions to …
constraints. How epithelia respond to and cope with disturbances of barrier functions to …