User profiles for Roland Stocker
Roland StockerHeart Research Institute Verified email at hri.org.au Cited by 49885 |
Bilirubin is an antioxidant of possible physiological importance
R Stocker, Y Yamamoto, AF McDonagh, AN Glazer… - Science, 1987 - science.org
Bilirubin, the end product of heme catabolism in mammals, is generally regarded as a
potentially cytotoxic, lipid-soluble waste product that needs to be excreted. However, it is shown …
potentially cytotoxic, lipid-soluble waste product that needs to be excreted. However, it is shown …
Role of oxidative modifications in atherosclerosis
R Stocker, JF Keaney Jr - Physiological reviews, 2004 - journals.physiology.org
This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …
Biochemistry and pathology of radical-mediated protein oxidation
Radical-mediated damage to proteins may be initiated by electron leakage, metal-ion-dependent
reactions and autoxidation of lipids and sugars. The consequent protein oxidation is O …
reactions and autoxidation of lipids and sugars. The consequent protein oxidation is O …
Antioxidant defenses and lipid peroxidation in human blood plasma.
The temporal disappearance in human blood plasma of endogenous antioxidants in
relation to the appearance of various classes of lipid hydroperoxides measured by HPLC …
relation to the appearance of various classes of lipid hydroperoxides measured by HPLC …
Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol.
The temporal disappearance of natural antioxidants associated with human low density
lipoprotein (LDL) in relation to the appearance of various classes of lipid hydroperoxides was …
lipoprotein (LDL) in relation to the appearance of various classes of lipid hydroperoxides was …
Antioxidant activity of albumin-bound bilirubin.
Bilirubin, when bound to human albumin and at concentrations present in normal human
plasma, protects albumin-bound linoleic acid from peroxyl radical-induced oxidation in vitro. …
plasma, protects albumin-bound linoleic acid from peroxyl radical-induced oxidation in vitro. …
Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein
Oxidation of human low-density lipoprotein (LDL) is implicated as an initiator of atherosclerosis.
a-Tocopherol (a-TocH) may thus inhibit atherosclerosis because it is the major and most …
a-Tocopherol (a-TocH) may thus inhibit atherosclerosis because it is the major and most …
Clinical relevance of biomarkers of oxidative stress
…, N Zarkovic, SS Davies, R Stocker… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Oxidative stress is considered to be an important component of various diseases.
A vast number of methods have been developed and used in virtually all diseases to …
A vast number of methods have been developed and used in virtually all diseases to …
[HTML][HTML] Free and albumin-bound bilirubin are efficient co-antioxidants for alpha-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation
J Neuzil, R Stocker - Journal of Biological Chemistry, 1994 - Elsevier
Peroxidation of the lipid moieties of low density lipoproteins (LDL) is regarded as an early
event in atherogenesis. Because bilirubin is a physiological reductant with antioxidant activities…
event in atherogenesis. Because bilirubin is a physiological reductant with antioxidant activities…
Presence of hypochlorite-modified proteins in human atherosclerotic lesions.
…, D Flowers, G Waeg, E Malle, R Stocker - The Journal of …, 1996 - Am Soc Clin Investig
Oxidation of LDL may contribute to atherogenesis, though the nature of the in vivo oxidant(s)
remains obscure. Myeloperoxidase, the enzyme responsible for hypochlorous acid/…
remains obscure. Myeloperoxidase, the enzyme responsible for hypochlorous acid/…