User profiles for Roland Stocker

Roland Stocker

Heart Research Institute
Verified email at hri.org.au
Cited by 49885

Bilirubin is an antioxidant of possible physiological importance

R Stocker, Y Yamamoto, AF McDonagh, AN Glazer… - Science, 1987 - science.org
Bilirubin, the end product of heme catabolism in mammals, is generally regarded as a
potentially cytotoxic, lipid-soluble waste product that needs to be excreted. However, it is shown …

Role of oxidative modifications in atherosclerosis

R Stocker, JF Keaney Jr - Physiological reviews, 2004 - journals.physiology.org
This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

Biochemistry and pathology of radical-mediated protein oxidation

RT Dean, S FU, R Stocker, MJ Davies - Biochemical Journal, 1997 - portlandpress.com
Radical-mediated damage to proteins may be initiated by electron leakage, metal-ion-dependent
reactions and autoxidation of lipids and sugars. The consequent protein oxidation is O …

Antioxidant defenses and lipid peroxidation in human blood plasma.

B Frei, R Stocker, BN Ames - Proceedings of the National …, 1988 - National Acad Sciences
The temporal disappearance in human blood plasma of endogenous antioxidants in
relation to the appearance of various classes of lipid hydroperoxides measured by HPLC …

Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol.

R Stocker, VW Bowry, B Frei - Proceedings of the National …, 1991 - National Acad Sciences
The temporal disappearance of natural antioxidants associated with human low density
lipoprotein (LDL) in relation to the appearance of various classes of lipid hydroperoxides was …

Antioxidant activity of albumin-bound bilirubin.

R Stocker, AN Glazer, BN Ames - Proceedings of the …, 1987 - National Acad Sciences
Bilirubin, when bound to human albumin and at concentrations present in normal human
plasma, protects albumin-bound linoleic acid from peroxyl radical-induced oxidation in vitro. …

Tocopherol-mediated peroxidation. The prooxidant effect of vitamin E on the radical-initiated oxidation of human low-density lipoprotein

VW Bowry, R Stocker - Journal of the American Chemical Society, 1993 - ACS Publications
Oxidation of human low-density lipoprotein (LDL) is implicated as an initiator of atherosclerosis.
a-Tocopherol (a-TocH) may thus inhibit atherosclerosis because it is the major and most …

Clinical relevance of biomarkers of oxidative stress

…, N Zarkovic, SS Davies, R Stocker… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Oxidative stress is considered to be an important component of various diseases.
A vast number of methods have been developed and used in virtually all diseases to …

[HTML][HTML] Free and albumin-bound bilirubin are efficient co-antioxidants for alpha-tocopherol, inhibiting plasma and low density lipoprotein lipid peroxidation

J Neuzil, R Stocker - Journal of Biological Chemistry, 1994 - Elsevier
Peroxidation of the lipid moieties of low density lipoproteins (LDL) is regarded as an early
event in atherogenesis. Because bilirubin is a physiological reductant with antioxidant activities…

Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

…, D Flowers, G Waeg, E Malle, R Stocker - The Journal of …, 1996 - Am Soc Clin Investig
Oxidation of LDL may contribute to atherogenesis, though the nature of the in vivo oxidant(s)
remains obscure. Myeloperoxidase, the enzyme responsible for hypochlorous acid/…