User profiles for Ronak Patel
 | Ronak PatelResearch Specialist, HHMI-Janelia Research Campus Verified email at janelia.hhmi.org Cited by 6661 |
Neurocircuitry models of posttraumatic stress disorder and beyond: a meta-analysis of functional neuroimaging studies
Over the past two decades a relatively large number of studies have investigated the
functional neuroanatomy of posttraumatic stress disorder (PTSD). However, findings are often …
functional neuroanatomy of posttraumatic stress disorder (PTSD). However, findings are often …
[HTML][HTML] Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics
Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience.
Here we describe red, single-wavelength GECIs, “RCaMPs,” engineered from circular …
Here we describe red, single-wavelength GECIs, “RCaMPs,” engineered from circular …
A general method to improve fluorophores for live-cell and single-molecule microscopy
Specific labeling of biomolecules with bright fluorophores is the keystone of fluorescence
microscopy. Genetically encoded self-labeling tag proteins can be coupled to synthetic dyes …
microscopy. Genetically encoded self-labeling tag proteins can be coupled to synthetic dyes …
High-performance calcium sensors for imaging activity in neuronal populations and microcompartments
Calcium imaging with genetically encoded calcium indicators (GECIs) is routinely used to
measure neural activity in intact nervous systems. GECIs are frequently used in one of two …
measure neural activity in intact nervous systems. GECIs are frequently used in one of two …
Sensitive red protein calcium indicators for imaging neural activity
10.7554/eLife.12727.001 Genetically encoded calcium indicators (GECIs) allow measurement
of activity in large populations of neurons and in small neuronal compartments, over times …
of activity in large populations of neurons and in small neuronal compartments, over times …
[PDF][PDF] Performance of ACMG-AMP variant-interpretation guidelines among nine laboratories in the clinical sequencing exploratory research consortium
…, A Milosavljevic, J Ou, CM Pak, RY Patel… - The American Journal of …, 2016 - cell.com
Evaluating the pathogenicity of a variant is challenging given the plethora of types of genetic
evidence that laboratories consider. Deciding how to weigh each type of evidence is difficult…
evidence that laboratories consider. Deciding how to weigh each type of evidence is difficult…
[HTML][HTML] Fast and sensitive GCaMP calcium indicators for imaging neural populations
Calcium imaging with protein-based indicators 1 , 2 is widely used to follow neural activity in
intact nervous systems, but current protein sensors report neural activity at timescales much …
intact nervous systems, but current protein sensors report neural activity at timescales much …
A general method to fine-tune fluorophores for live-cell and in vivo imaging
Pushing the frontier of fluorescence microscopy requires the design of enhanced
fluorophores with finely tuned properties. We recently discovered that incorporation of four-membered …
fluorophores with finely tuned properties. We recently discovered that incorporation of four-membered …
[HTML][HTML] The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
The International Human Epigenome Consortium (IHEC) coordinates the generation of a
catalog of high-resolution reference epigenomes of major primary human cell types. The …
catalog of high-resolution reference epigenomes of major primary human cell types. The …
Labeling of active neural circuits in vivo with designed calcium integrators
The identification of active neurons and circuits in vivo is a fundamental challenge in understanding
the neural basis of behavior. Genetically encoded calcium (Ca 2+ ) indicators (GECIs…
the neural basis of behavior. Genetically encoded calcium (Ca 2+ ) indicators (GECIs…