This study evaluated a rapid biomineralization phenomenon exhibited by an osteoblastic cell
line, UMR 106-01 BSP, when treated with either organic phosphates [β-glycerophosphate (…

Human bone marrow was harvested by means of iliac crest aspiration and cultured under
conditions that promote an osteoblastic phenotype. Human bone marrow aspirates from 30 …

Tissue engineering can be defined as any effort to create or induce the formation of a specific
tissue in a specific location through the selection and manipulation of cells, matrices, and …

Hyaluronan and chondroitin/dermatan sulfate are glycosaminoglycans that play major roles
in the biomechanical properties of a wide variety of tissues, including cartilage. A chondroitin/…

This study tested the hypothesis that pulsed electromagnetic field (PEMF) treatments
augment and accelerate the healing of bone trauma. It utilized micro‐computed tomography …

The circadian clock is an endogenous time keeping system that controls the physiology and
behavior of many organisms. The transcription factor Brain and Muscle ARNT-like Protein 1 (…

Porcine bioprosthetic heart valves degenerate and fail mechanically through a mechanism
that is currently not well understood. It has been suggested that damage to the elastin …

Stem cell activation and development is central to skeletal development, maintenance, and
repair, as it is for all tissues. However, an integrated model of stem cell proliferation, …

α V β 3 , a broadly distributed member of the integrin family of adhesion receptors, has been
implicated in a variety of physiological and pathophysiological events, including control of …

The extracellular matrix glycosaminoglycan, hyaluronan, has been described as a regulator
of tissue inflammation, with hyaluronan fragments reported to stimulate innate immune cells. …