[HTML][HTML] Genome wide screen of RNAi molecules against SARS-CoV-2 creates a broadly potent prophylaxis
…, A Naamti, I Falciatori, AC Berkyurek, R Rasnic… - bioRxiv, 2022 - ncbi.nlm.nih.gov
Expanding the arsenal of prophylactic approaches against SARS-CoV-2 is of utmost
importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we …
importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we …
[HTML][HTML] Chromoanagenesis landscape in 10,000 TCGA patients
R Rasnic, M Linial - Cancers, 2021 - mdpi.com
Simple Summary Chromoanagenesis is a single catastrophic event in which one or few
chromosomes are shattered and disorderly reassembled. Chromoanagenesis is common in …
chromosomes are shattered and disorderly reassembled. Chromoanagenesis is common in …
[HTML][HTML] Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants
Background In recent years, research on cancer predisposition germline variants has emerged
as a prominent field. The identity of somatic mutations is based on a reliable mapping of …
as a prominent field. The identity of somatic mutations is based on a reliable mapping of …
[HTML][HTML] Expanding cancer predisposition genes with ultra-rare cancer-exclusive human variations
It is estimated that up to 10% of cancer incidents are attributed to inherited genetic
alterations. Despite extensive research, there are still gaps in our understanding of genetic …
alterations. Despite extensive research, there are still gaps in our understanding of genetic …
Enhancing identification of cancer types via lowly-expressed microRNAs
The primary function of microRNAs (miRNAs) is to maintain cell homeostasis. In cancerous
tissues miRNAs’ expression undergo drastic alterations. In this study, we use miRNA …
tissues miRNAs’ expression undergo drastic alterations. In this study, we use miRNA …
Characteristics of myeloproliferative neoplasms in patients exposed to ionizing radiation following the Chernobyl nuclear accident
…, M Adam, E Fraenkel, R Rasnic… - American journal of …, 2019 - Wiley Online Library
Myeloproliferative neoplasms (MPNs) driver mutations are usually found in JAK2, MPL, and
CALR genes; however, 10%‐15% of cases are triple negative (TN). A previous study …
CALR genes; however, 10%‐15% of cases are triple negative (TN). A previous study …
A scalable pipeline for SARS-CoV-2 replicon construction based on de-novo synthesis
AC Berkyurek, E Lee, O Weissbrod, R Rasnic… - bioRxiv, 2022 - biorxiv.org
Replicons are synthetic viral RNA molecules that recapitulate the self-replicating activities of
the virus but are missing its infectivity potential. Here, we report on a scalable pipeline to …
the virus but are missing its infectivity potential. Here, we report on a scalable pipeline to …
[HTML][HTML] From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis
…, I Falciatori, AC Berkyurek, R Rasnic… - Communications …, 2023 - nature.com
Expanding the arsenal of prophylactic approaches against SARS-CoV-2 is of utmost
importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we …
importance, specifically those strategies that are resistant to antigenic drift in Spike. Here, we …
Reduced Mortality During Holidays and the COVID-19 Pandemic in Israel
Evidence suggests varied trends in mortality surrounding the holiday period. Most studies
support an association between increased mortality rates and holidays. We compare the effect …
support an association between increased mortality rates and holidays. We compare the effect …
Lowest expressing microRNAs capture indispensable information: identifying cancer types
The primary function of microRNAs (miRNAs) is to maintain cell homeostasis. In cancerous
tissues miRNAs’ expression undergo drastic alterations. In this study, we used miRNA …
tissues miRNAs’ expression undergo drastic alterations. In this study, we used miRNA …